Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26700639 | 0.82 | MEN1 (0.42) | KDM4EALDH1A1MEN1KMT2AFAAH | |
| SCHEMBL13884348 | 0.82 | MEN1 (0.42) | KDM4EALDH1A1MEN1KMT2AFAAH | |
| SCHEMBL25109878 | 0.82 | MEN1 (0.42) | KDM4EALDH1A1MEN1KMT2AFAAH | |
| SCHEMBL17446604 | 0.82 | MEN1 (0.42) | KDM4EALDH1A1MEN1KMT2AFAAH | |
| SCHEMBL20332107 | 0.82 | MEN1 (0.42) | KDM4EALDH1A1MEN1KMT2AFAAH | |
| SCHEMBL12438086 | 0.80 | MEN1 (0.39) | KDM4EALDH1A1MEN1KMT2AFAAH | |
| SCHEMBL842217 | 0.79 | ALDH1A1 (0.43) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL840536 | 0.79 | ALDH1A1 (0.43) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL8279517 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL25483586 | 0.79 | MEN1 (0.36) | MEN1KMT2AFAAHMAPK1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160192-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |