SCHEMBL2230600

SCHEMBL2230600

CCCCCCCCCCCCC(CCN)CCN

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.54
DNM1 Q05193 9/20 0.52
ALDH1A1 P00352 2/20 0.52
TSHR P16473 2/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
EPHX1 P07099 1/20 0.52
SPHK1 Q9NYA1 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
OPRM1 P35372 1/20 0.46
THRB P10828 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9513225 1.00 LMNA (0.54) LMNADNM1ALDH1A1TSHRMEN1
SCHEMBL14840420 1.00 LMNA (0.54) LMNADNM1ALDH1A1TSHRMEN1
SCHEMBL5870603 1.00 LMNA (0.54) LMNADNM1ALDH1A1TSHRMEN1
SCHEMBL25469862 1.00 LMNA (0.54) LMNADNM1ALDH1A1TSHRMEN1
SCHEMBL14839987 1.00 LMNA (0.54) LMNADNM1ALDH1A1TSHRMEN1
SCHEMBL23586497 1.00 LMNA (0.54) LMNADNM1ALDH1A1TSHRMEN1
SCHEMBL14839929 1.00 LMNA (0.54) LMNADNM1ALDH1A1TSHRMEN1
SCHEMBL19119422 1.00 LMNA (0.54) LMNADNM1ALDH1A1TSHRMEN1
SCHEMBL10460520 1.00 LMNA (0.54) LMNADNM1ALDH1A1TSHRMEN1
SCHEMBL5511023 1.00 LMNA (0.54) LMNADNM1ALDH1A1TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283550-A1 AMIDINE-GROUP CONTAINING CATALYST Sika Technology AG (CH) 2018-02-21 EP disclosed
WO-2016166336-A1 AMIDINE-GROUP CONTAINING CATALYST SIKA TECHNOLOGY AG (CH) 2016-10-20 WO disclosed
EP-2132248-B1 ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN SIKA TECHNOLOGY AG (CH) 2016-07-13 EP disclosed
EP-2200973-B1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE SIKA TECHNOLOGY AG (CH) 2011-07-13 EP disclosed
EP-2200973-A1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE Sika Technology AG (CH) 2010-06-30 EP disclosed
EP-2178828-A1 ALDIMINES AND COMPOSITIONS COMPRISING ALDAMINE Sika Technology AG (CH) 2010-04-28 EP disclosed
EP-2145907-A1 Amorphous polyurethane polymer and use thereof in hotmelt adhesives Sika Technology AG (CH) 2010-01-20 EP disclosed
EP-2132248-A1 ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN Sika Technology AG (CH) 2009-12-16 EP disclosed
EP-2089447-A1 POLYURETHANE COMPOSITION WITH GOOD INITIAL STRENGTH Sika Technology AG (CH) 2009-08-19 EP disclosed
WO-2009027511-A1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE SIKA TECHNOLOGY AG (CH) 2009-03-05 WO disclosed
EP-2030967-A1 Aldimines containing hydroxyl groups and compositions containing aldimine Sika Technology AG (CH) 2009-03-04 EP disclosed
WO-2009010522-A1 ALDIMINES AND COMPOSITIONS COMPRISING ALDAMINE SIKA TECHNOLOGY AG (CH) 2009-01-22 WO disclosed
EP-2017260-A1 Aldimines and compounds containing aldimine Sika Technology AG (CH) 2009-01-21 EP disclosed
WO-2008116928-A1 ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN SIKA TECHNOLOGY AG (CH) 2008-10-02 WO disclosed
WO-2008052999-A1 POLYURETHANE COMPOSITION WITH GOOD INITIAL STRENGTH SIKA TECHNOLOGY AG (CH) 2008-05-08 WO disclosed
EP-1918314-A1 Polyurethane composition with high green strength Sika Technology AG (CH) 2008-05-07 EP disclosed