SCHEMBL22306014

SCHEMBL22306014

C=CCC(CCC)C(N)=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CHRM1 P11229 1/20 0.43
AKR1A1 P14550 1/20 0.43
CHRM3 P20309 1/20 0.43
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
ADRA1A P35348 1/20 0.43
HRH1 P35367 1/20 0.43
DRD3 P35462 1/20 0.43
SLC6A3 Q01959 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC2 Q92769 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
TSHR P16473 4/20 0.41
CYP3A4 P08684 3/20 0.41
NFKB1 P19838 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
GRIK1 P39086 3/20 0.41
GRIK2 Q13002 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17343614 1.00 CA1 (0.45) CA1CA2CHRM1AKR1A1CHRM3
SCHEMBL28191059 0.88 CA2 (0.62) CA1CA2TSHRCYP3A4GRIK1
SCHEMBL26088512 0.87 GRIK1 (0.47) CA1CA2SLC6A3TSHRNFKB1
SCHEMBL4019615 0.85 CA2 (0.53) CA1CA2TSHRCYP3A4GRIK1
SCHEMBL30197469 0.85 CA2 (0.53) CA1CA2TSHRCYP3A4GRIK1
SCHEMBL10441902 0.85 CA2 (0.53) CA1CA2TSHRCYP3A4GRIK1
SCHEMBL4013782 0.85 CA2 (0.53) CA1CA2TSHRCYP3A4GRIK1
SCHEMBL28209930 0.85 CA2 (0.53) CA1CA2TSHRCYP3A4GRIK1
SCHEMBL27448303 0.85 CA2 (0.53) CA1CA2TSHRCYP3A4GRIK1
SCHEMBL28373909 0.83 CA2 (0.52) CA1CA2TSHRCYP3A4GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117378604-A Pesticide composition for stem and leaf treatment 组合化学工业株式会社 2024-01-12 CN disclosed
WO-2020160192-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2020-08-06 WO disclosed