Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23925429 | 0.83 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2ALDH1A1GRM5 | |
| SCHEMBL30197965 | 0.83 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2ALDH1A1GRM5 | |
| SCHEMBL30198406 | 0.83 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2ALDH1A1GRM5 | |
| SCHEMBL23952301 | 0.83 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2ALDH1A1GRM5 | |
| SCHEMBL12090844 | 0.75 | POLB (0.51) | MEN1KMT2ASMN1; SMN2ALDH1A1GRM5 | |
| SCHEMBL23952250 | 0.74 | MEN1 (0.34) | MEN1KMT2ASMN1; SMN2ALDH1A1GRM5 | |
| SCHEMBL30197589 | 0.74 | MEN1 (0.34) | MEN1KMT2ASMN1; SMN2ALDH1A1GRM5 | |
| SCHEMBL14585663 | 0.73 | TNKS (0.36) | MEN1KMT2ASMN1; SMN2DRD2GAA | |
| SCHEMBL12038178 | 0.71 | MEN1 (0.54) | MEN1KMT2AGRM5 | |
| SCHEMBL13139310 | 0.71 | HTR2A (0.44) | MEN1KMT2ASMN1; SMN2GRM5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |
| WO-2020160180-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |