Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23952250 | 1.00 | MEN1 (0.34) | MEN1KMT2AGRM5ALDH1A1SMN1; SMN2 | |
| SCHEMBL23925455 | 0.86 | POLB (0.36) | MEN1KMT2AGRM5POLBRECQL | |
| SCHEMBL30197563 | 0.86 | POLB (0.36) | MEN1KMT2AGRM5POLBRECQL | |
| SCHEMBL23977617 | 0.83 | — | — | |
| SCHEMBL22306172 | 0.74 | MEN1 (0.42) | MEN1KMT2AGRM5ALDH1A1SMN1; SMN2 | |
| SCHEMBL23925429 | 0.71 | MEN1 (0.41) | MEN1KMT2AGRM5ALDH1A1SMN1; SMN2 | |
| SCHEMBL30197965 | 0.71 | MEN1 (0.41) | MEN1KMT2AGRM5ALDH1A1SMN1; SMN2 | |
| SCHEMBL30198406 | 0.71 | MEN1 (0.41) | MEN1KMT2AGRM5ALDH1A1SMN1; SMN2 | |
| SCHEMBL23952301 | 0.71 | MEN1 (0.41) | MEN1KMT2AGRM5ALDH1A1SMN1; SMN2 | |
| SCHEMBL2043461 | 0.69 | MEN1 (0.43) | MEN1KMT2AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4135691-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X4 AND RELATED PRODUCTS AND METHODS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-02-22 | — | — | EP | disclosed |