Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | CPA1 | P15085 | 2/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20444166 | 0.78 | MME (0.35) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL597622 | 0.78 | ALDH1A1 (0.53) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL22305848 | 0.78 | ALDH1A1 (0.38) | ALDH1A1TDP1 | |
| SCHEMBL26292991 | 0.76 | — | — | |
| SCHEMBL7081089 | 0.76 | — | — | |
| SCHEMBL26292989 | 0.76 | — | — | |
| SCHEMBL24915091 | 0.75 | — | — | |
| SCHEMBL7967722 | 0.75 | — | — | |
| SCHEMBL1659486 | 0.75 | MME (0.37) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL1659488 | 0.75 | MME (0.37) | MMEACECPA1ACE2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160192-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |