Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 5/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | TAF1 | P21675 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.35 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM6A | O15550 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3341729 | 0.81 | GAA (0.42) | GAABRD4PTPN1BRD9MTNR1A | |
| SCHEMBL24207286 | 0.81 | GAA (0.42) | GAABRD4PTPN1BRD9MTNR1A | |
| SCHEMBL24204511 | 0.78 | GAA (0.41) | GAABRD4PTPN1BRD9MTNR1A | |
| SCHEMBL17621624 | 0.76 | BRD4 (0.41) | GAABRD4PTPN1BRD9TAF1 | |
| SCHEMBL13833580 | 0.76 | GAA (0.57) | GAABRD4PTPN1BRD9BRD7 | |
| Hydrochloric Acid SCHEMBL30032118 | 0.74 | BRD4 (0.39) | GAABRD4PTPN1BRD9TAF1 | |
| SCHEMBL14502422 | 0.72 | KDM4E (0.41) | PTPN1PDE3BPDE3AMAPTKDM4E | |
| SCHEMBL597709 | 0.72 | TSHR (0.52) | GAAPDE3BPDE3AKDM4ECYP1A2 | |
| SCHEMBL22306208 | 0.71 | TP53 (0.42) | GAABRD4BRD9TAF1BRPF1 | |
| SCHEMBL10050973 | 0.71 | BRD9 (0.42) | BRD4PTPN1BRD9PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160180-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |