Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15184496 | 0.85 | KDM4A (0.43) | TDP1CA1CA2LMNACA12 | |
| SCHEMBL19770197 | 0.83 | HTT (0.44) | HTTNPSR1NQO2TDP1MAPT | |
| SCHEMBL30466794 | 0.82 | HPGD (0.49) | HTTNPSR1NQO2TDP1MAPT | |
| SCHEMBL30466788 | 0.81 | HTT (0.42) | HTTNPSR1NQO2TDP1MAPT | |
| SCHEMBL30466778 | 0.80 | MALT1 (0.43) | HTTNPSR1NQO2TDP1MAPT | |
| SCHEMBL25746081 | 0.79 | MAPT (0.41) | HTTNPSR1NQO2TDP1MAPT | |
| SCHEMBL22307372 | 0.77 | NPSR1 (0.40) | HTTNPSR1NQO2TDP1MAPT | |
| SCHEMBL22290822 | 0.77 | USP30 (0.44) | HTTNPSR1NQO2TDP1MAPT | |
| SCHEMBL21751228 | 0.77 | DPP4 (0.46) | HTTNPSR1NQO2MAPTLMNA | |
| SCHEMBL6184762 | 0.75 | NPC1 (0.56) | HTTNQO2MAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160075-A1 | CHEMICAL COMPOUNDS | AVISTA PHARMA SOLUTIONS, INC. (US) | 2020-08-06 | — | — | WO | disclosed |