Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19190653 | 0.80 | CA2 (0.47) | HTTNQO2NAMPTTDP1MAPT | |
| SCHEMBL22306558 | 0.77 | HTT (0.44) | NPSR1HTTNQO2NAMPTTDP1 | |
| SCHEMBL19770197 | 0.75 | HTT (0.44) | NPSR1HTTNQO2NAMPTTDP1 | |
| SCHEMBL30466794 | 0.74 | HPGD (0.49) | NPSR1HTTNQO2NAMPTTDP1 | |
| SCHEMBL19263488 | 0.73 | CA12 (0.57) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL30466788 | 0.73 | HTT (0.42) | NPSR1HTTNQO2NAMPTTDP1 | |
| SCHEMBL17732865 | 0.72 | L3MBTL1 (0.46) | NPSR1NAMPTTDP1MAPTCA1 | |
| SCHEMBL30466778 | 0.72 | MALT1 (0.43) | NPSR1HTTNQO2NAMPTTDP1 | |
| SCHEMBL22290822 | 0.71 | USP30 (0.44) | NPSR1HTTNQO2NAMPTTDP1 | |
| SCHEMBL12461268 | 0.71 | CA12 (0.58) | TDP1CA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230029009-A1 | CHEMICAL COMPOUNDS | BLUE OWL CAPITAL CORPORATION, AS NEW AGENT | 2023-01-26 | — | — | US | disclosed |
| US-20200270257-A1 | Chemical Compounds | BLUE OWL CAPITAL CORPORATION, AS NEW AGENT | 2020-08-27 | — | — | US | disclosed |
| WO-2020160075-A1 | CHEMICAL COMPOUNDS | AVISTA PHARMA SOLUTIONS, INC. (US) | 2020-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230029009-A1 | CHEMICAL COMPOUNDS | PTGER4, PTGES, PTGES2 | NPSR1 124/4885HTT 4172/4885NQO2 1730/4885 |
| US-20200270257-A1 | Chemical Compounds | PTGER4, PTGES, PTGES2 | NPSR1 124/4885HTT 4172/4885NQO2 1730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.