Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 4/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22290783 | 0.82 | MAOB (0.51) | PKMMAOAMAOB | |
| SCHEMBL31173265 | 0.82 | MAOB (0.51) | PKMMAOAMAOB | |
| SCHEMBL12970421 | 0.81 | PKM (0.59) | PKMADORA3JMJD6ADORA2AADORA1 | |
| SCHEMBL12970186 | 0.72 | PKM (0.42) | PKMMAOAMAOB | |
| SCHEMBL19253512 | 0.71 | APP (0.47) | MAOB | |
| SCHEMBL17279830 | 0.69 | BRD4 (0.48) | PKMFFAR1GRM5HRH4MAOA | |
| SCHEMBL2629335 | 0.68 | — | — | |
| SCHEMBL14082762 | 0.68 | IDO1 (0.41) | FFAR1MAOB | |
| SCHEMBL17591456 | 0.67 | F10 (0.54) | FFAR1MAOAMAOB | |
| SCHEMBL7810321 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160180-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |