SCHEMBL2230679

SCHEMBL2230679

O=C(NO)c1cccc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 3/20 1.00
MMP3 P08254 1/20 1.00
PLK1 P53350 1/20 0.69
HDAC1 Q13547 2/20 0.64
HDAC6 Q9UBN7 2/20 0.64
HDAC3 O15379 1/20 0.64
HDAC4 P56524 1/20 0.64
HDAC7 Q8WUI4 1/20 0.64
HDAC2 Q92769 1/20 0.64
HDAC10 Q969S8 1/20 0.64
HDAC11 Q96DB2 1/20 0.64
HDAC9 Q9UKV0 1/20 0.64
HDAC5 Q9UQL6 1/20 0.64
NR4A1 P22736 1/20 0.61
NR4A2 P43354 1/20 0.61
NR4A3 Q92570 1/20 0.61
DEGS1 O15121 1/20 0.59
PLAU P00749 1/20 0.58
NPC1 O15118 1/20 0.57
RAB9A P51151 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29816659 1.00 HDAC8 (1.00) HDAC8MMP3PLK1HDAC1HDAC6
SCHEMBL7872561 1.00 HDAC8 (1.00) HDAC8MMP3PLK1HDAC1HDAC6
Sulfuric Acid SCHEMBL28957208 0.93 HDAC8 (0.86) HDAC8MMP3PLK1HDAC1HDAC6
Pyrrole SCHEMBL6531752 0.89 HDAC8 (0.80) HDAC8MMP3PLK1HDAC1HDAC6
SCHEMBL28965001 0.85 HDAC8 (0.73) HDAC8MMP3PLK1HDAC1HDAC6
SCHEMBL1605906 0.85 HDAC8 (0.74) HDAC8MMP3PLK1HDAC1HDAC6
SCHEMBL6635701 0.85 MMP3 (0.74) HDAC8MMP3PLK1NR4A1NR4A2
SCHEMBL145153 0.82 HDAC8 (0.69) HDAC8MMP3PLK1HDAC1HDAC6
SCHEMBL8191199 0.82 PLK1 (1.00) HDAC8MMP3PLK1HDAC1HDAC6
SCHEMBL10997796 0.82 HDAC8 (0.69) HDAC8MMP3PLK1HDAC1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120195305-A Method for quantitatively characterizing adsorption quantity of carboxylate and hydroxamic acid medicament on mineral surface 西南科技大学 2025-06-24 CN claimed
CN-119140283-A Beneficiation method for comprehensively recovering lithium beryllium resources in fluorite tailings 中南大学 2024-12-17 CN claimed
CN-118768091-A Method for strengthening flotation separation of micro-fine rare earth ore 内蒙古科技大学 2024-10-15 CN claimed
EP-4410284-A1 COMPOUND AND METHOD FOR THE TREATMENT OF ZELLWEGER SPECTRUM DISORDER Apteeus (FR) 2024-08-07 EP claimed
CN-117960394-A Flotation collector and application thereof in low-grade spodumene 长沙立孚资环科技有限公司 2024-05-03 CN claimed
CN-115959692-B Method for extracting lithium sodium potassium fluoroaluminate from solid volatile matters of aluminum electrolysis cell 中铝郑州有色金属研究院有限公司 2024-03-12 CN claimed
CN-117414940-A Method for floatation co-enrichment of tungsten ore and rutile 中南大学 2024-01-19 CN claimed
CN-117317366-A Electrolyte for lithium iron phosphate large cylindrical battery and battery 南京中比新能源科技有限公司 2023-12-29 CN claimed
CN-116727109-A Method for separating iron-containing silicate gangue minerals by reverse flotation of chelating collector 安徽工业大学 2023-09-12 CN claimed
WO-2023143608-A1 COMPOSITION, METHOD FOR PREPARING SAME, AND USE THEREOF 上海复东生物医药有限责任公司 2023-08-03 WO claimed
CN-101300345-A Aggrecanase structure WYETH CORP (US) 2008-11-05 CN claimed
EP-1917354-A2 AGGRECANASE STRUCTURE Wyeth (US) 2008-05-07 EP claimed
US-20070178574-A1 AGGRECANASE STRUCTURE WYETH (US) 2007-08-02 US claimed
JP-2007516982-A 2007-06-28 JP claimed
WO-2007025248-A2 AGGRECANASE STRUCTURE WYETH (US) 2007-03-01 WO claimed
EP-1694410-A2 CYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF Japan Tobacco, Inc. (JP) 2006-08-30 EP claimed
WO-2005058884-A2 CYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2005-06-30 WO claimed
EP-0095899-B1 COLOR-FORMING CARBOXAMIDONAPHTHALENE DYE PRECURSOR COMPOUNDS, PHOTOGRAPHIC MATERIALS CONTAINING THEM AND CORRESPONDING CARBOXIMIDE DYES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-08-20 EP claimed
EP-0034497-B1 ELECTROPHOTOGRAPHIC LIGHT-SENSITIVE MEDIA Canon Inc. (JP) 1985-09-11 EP claimed
US-4076530-A Dry photographic copying method for producing Te images FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US claimed