Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231742 | 0.84 | TAAR1 (0.43) | KMT2ATDP1TAAR1HSP90AA1MAPT | |
| SCHEMBL2230629 | 0.83 | KMT2A (0.45) | KMT2ATDP1TAAR1HSP90AA1LMNA | |
| SCHEMBL636142 | 0.83 | TAAR1 (0.42) | KMT2ATDP1TAAR1HSP90AA1MAPT | |
| SCHEMBL638109 | 0.82 | KMT2A (0.44) | KMT2ATDP1TAAR1HSP90AA1LMNA | |
| SCHEMBL917267 | 0.82 | MEN1 (0.46) | KMT2ATAAR1HSP90AA1MAPTALDH1A1 | |
| SCHEMBL2231127 | 0.81 | ELANE (0.44) | KMT2ATDP1TAAR1HSP90AA1MAPT | |
| SCHEMBL637737 | 0.81 | GAA (0.52) | KMT2ATDP1TAAR1MAPTALDH1A1 | |
| SCHEMBL2231331 | 0.80 | TAAR1 (0.48) | KMT2ATDP1TAAR1HSP90AA1MAPT | |
| SCHEMBL915659 | 0.80 | TAAR1 (0.40) | KMT2ATDP1TAAR1HSP90AA1MAPT | |
| SCHEMBL637464 | 0.80 | ELANE (0.43) | KMT2ATDP1TAAR1HSP90AA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2354120-A1 | Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof | XenoPort, Inc. (US) | 2011-08-10 | — | — | EP | disclosed |