Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 5/20 | 0.51 |
| ▸ | CA1 | P00915 | 7/20 | 0.48 |
| ▸ | CA2 | P00918 | 7/20 | 0.48 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | STK17B | O94768 | 1/20 | 0.44 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10329432 | 0.84 | CA1 (0.54) | GAAKDM4EALDH1A1GLAMAPT | |
| SCHEMBL2231127 | 0.82 | ELANE (0.44) | ALDH1A1MAPTTDP1TAAR1KMT2A | |
| SCHEMBL2230682 | 0.81 | KMT2A (0.49) | ALDH1A1MAPTTDP1TAAR1KMT2A | |
| SCHEMBL637464 | 0.81 | ELANE (0.43) | ALDH1A1MAPTTDP1TAAR1KMT2A | |
| SCHEMBL916412 | 0.81 | KMT2A (0.43) | ALDH1A1MAPTTDP1TAAR1KMT2A | |
| SCHEMBL2231640 | 0.81 | TAAR1 (0.44) | ALDH1A1MAPTTDP1TAAR1KMT2A | |
| SCHEMBL27698153 | 0.80 | ALDH1A1 (0.53) | GAAKDM4EALDH1A1GLAMAPT | |
| SCHEMBL917452 | 0.80 | KMT2A (0.42) | ALDH1A1MAPTTDP1TAAR1KMT2A | |
| SCHEMBL2231742 | 0.80 | TAAR1 (0.43) | ALDH1A1MAPTTDP1TAAR1KMT2A | |
| SCHEMBL639621 | 0.79 | ELANE (0.41) | ALDH1A1MAPTHPGDTDP1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660440-B1 | ACYLOXYALKYL CARBAMATE PRODRUGS, METHODS OF SYNTHESIS AND USE | XENOPORT INC (US) | 2012-02-22 | — | — | EP | disclosed |