Tetrabuthylammonium

Tetrabuthylammonium

SCHEMBL2230707

CCCC[N+](CCCC)(CCCC)CCCC.O=C([O-])CCCCCCCCC(=O)O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.63
PPARG P37231 7/20 0.63
PPARD Q03181 7/20 0.63
PPARA Q07869 7/20 0.63
HDAC11 Q96DB2 5/20 0.63
TSHR P16473 4/20 0.63
FABP3 P05413 4/20 0.63
PTPN1 P18031 3/20 0.63
ALDH1A1 P00352 2/20 0.63
TLR2 O60603 2/20 0.63
TDP1 Q9NUW8 2/20 0.63
FABP4 P15090 2/20 0.63
KMT2A Q03164 2/20 0.63
SLC22A6 Q4U2R8 1/20 0.63
SLC22A8 Q8TCC7 1/20 0.63
MEN1 O00255 1/20 0.63
ESR1 P03372 1/20 0.63
ALOX15 P16050 1/20 0.63
PDE4A P27815 1/20 0.63
PDE3A Q14432 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrabuthylammonium SCHEMBL104377 0.98 AKR1B1 (0.61) GPR84PPARGPPARDPPARAHDAC11
Tetrabuthylammonium SCHEMBL109358 0.94 AKR1B1 (0.56) GPR84PPARGPPARDPPARAHDAC11
Tetrabuthylammonium SCHEMBL8778043 0.92 FABP3 (0.62) FABP3
Tetrabuthylammonium SCHEMBL2230010 0.92 FABP3 (0.62) FABP3
Stearic Acid SCHEMBL4651821 0.92 FABP3 (0.62) FABP3
Tetrabuthylammonium SCHEMBL106487 0.92 FABP3 (0.62) FABP3
Stearic Acid SCHEMBL109143 0.92 FABP3 (0.62) FABP3
Behenic Acid SCHEMBL737441 0.92 FABP3 (0.62) FABP3
Tetrabuthylammonium SCHEMBL105341 0.92 FABP3 (0.62) FABP3
Tetrabuthylammonium SCHEMBL107918 0.92 FABP3 (0.62) FABP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111171364-A Force-responsive polymer foam particle and preparation method thereof 翁秋梅 2020-05-19 CN disclosed
US-20150307655-A1 Polyesters, Methods of Making Polyesters and Uses Therefor NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-10-29 US disclosed
US-9023972-B2 Polyesters, methods of making polyesters and uses therefor University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2015-05-05 US disclosed
US-20130071930-A1 POLYESTERS, METHODS OF MAKING POLYESTERS AND USES THEREFOR UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2013-03-21 US disclosed
WO-2011091411-A2 POLYESTERS, METHODS OF MAKING POLYESTERS AND USES THEREFOR UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2011-07-28 WO disclosed
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150307655-A1 Polyesters, Methods of Making Polyesters and Uses Therefor PUF60, HSD17B12, CYP46A1 GPR84 3131/4885PPARG 1713/4885PPARD 2526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.