Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.67 |
| ▸ | GSPT1 | P15170 | 3/20 | 0.55 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28737958 | 0.92 | CRBN (0.67) | CRBNGSPT1CSNK1A1 | |
| SCHEMBL26739486 | 0.91 | CRBN (0.66) | CRBNGSPT1 | |
| SCHEMBL26740208 | 0.87 | CRBN (0.61) | CRBNGSPT1 | |
| SCHEMBL24828772 | 0.87 | CRBN (0.69) | CRBNGSPT1 | |
| SCHEMBL26740201 | 0.86 | CRBN (0.60) | CRBNGSPT1 | |
| SCHEMBL24250681 | 0.86 | CRBN (0.68) | CRBNGSPT1 | |
| SCHEMBL27290606 | 0.86 | CRBN (0.59) | CRBNGSPT1CSNK1A1 | |
| SCHEMBL26740215 | 0.86 | CRBN (0.59) | CRBNGSPT1CSNK1A1 | |
| SCHEMBL26740198 | 0.86 | CRBN (0.59) | CRBNGSPT1CSNK1A1 | |
| SCHEMBL29739711 | 0.85 | CRBN (0.58) | CRBNGSPT1CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069720-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |