Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A1 | Q14973 | 8/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22307721 | 1.00 | SLC10A1 (0.51) | SLC10A1MAPK1GAAALDH1A1ALOX15 | |
| SCHEMBL28634542 | 1.00 | SLC10A1 (0.51) | SLC10A1MAPK1GAAALDH1A1ALOX15 | |
| SCHEMBL22307951 | 0.90 | SLC10A1 (0.53) | SLC10A1MAPK1GAAALDH1A1ALOX15 | |
| SCHEMBL28638214 | 0.90 | SLC10A1 (0.53) | SLC10A1MAPK1GAAALDH1A1ALOX15 | |
| SCHEMBL23224038 | 0.90 | SLC10A1 (0.52) | SLC10A1MAPK1ALDH1A1 | |
| SCHEMBL23224045 | 0.90 | SLC10A1 (0.52) | SLC10A1MAPK1ALDH1A1 | |
| SCHEMBL23223990 | 0.86 | SLC10A1 (0.55) | SLC10A1MAPK1 | |
| SCHEMBL23223989 | 0.86 | SLC10A1 (0.55) | SLC10A1MAPK1 | |
| SCHEMBL22307697 | 0.85 | SLC10A1 (0.54) | SLC10A1MAPK1 | |
| SCHEMBL23224036 | 0.85 | SLC10A1 (0.54) | SLC10A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113365999-B | Capsid protein assembly inhibitors containing pyrroloheterocycles | 正大天晴药业集团股份有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-113365999-A | Capsid protein assembly inhibitors containing pyrroloheterocycles | 正大天晴药业集团股份有限公司 | 2021-09-07 | — | — | CN | disclosed |
| WO-2020156494-A1 | CAPSID PROTEIN ASSEMBLY INHIBITOR CONTAINING PYRROLO HETEROCYCLE | 正大天晴药业集团股份有限公司 | 2020-08-06 | — | — | WO | disclosed |