SCHEMBL23224036

SCHEMBL23224036

CC(NC(=O)C(=O)c1c(Cl)c(C(=O)O)c2n1CCC2)C(F)(F)F

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC10A1 Q14973 16/20 0.54
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22307697 1.00 SLC10A1 (0.54) SLC10A1KMT2AKDM4EMAPK1
SCHEMBL22307722 1.00 SLC10A1 (0.54) SLC10A1KMT2AKDM4EMAPK1
SCHEMBL23223989 0.92 SLC10A1 (0.55) SLC10A1MAPK1
SCHEMBL23223990 0.92 SLC10A1 (0.55) SLC10A1MAPK1
SCHEMBL23224045 0.89 SLC10A1 (0.52) SLC10A1KMT2AMAPK1
SCHEMBL23224038 0.89 SLC10A1 (0.52) SLC10A1KMT2AMAPK1
SCHEMBL22307243 0.87 SLC10A1 (0.57) SLC10A1KDM4E
SCHEMBL28634538 0.87 SLC10A1 (0.57) SLC10A1KDM4E
SCHEMBL22307696 0.85 SLC10A1 (0.51) SLC10A1MAPK1
SCHEMBL22307721 0.85 SLC10A1 (0.51) SLC10A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113365999-B Capsid protein assembly inhibitors containing pyrroloheterocycles 正大天晴药业集团股份有限公司 2023-04-14 CN disclosed
CN-113365999-A Capsid protein assembly inhibitors containing pyrroloheterocycles 正大天晴药业集团股份有限公司 2021-09-07 CN disclosed
EP-3805223-A1 2,3-DIHYDRO-1H-PYRROLIZINE-7-FORMAMIDE DERIVATIVE AND APPLICATION THEREOF Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) 2021-04-14 EP disclosed