Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29473072 | 1.00 | MAPT (0.48) | MAPTRAB9AALDH1A1NPC1HPGD | |
| SCHEMBL30698534 | 0.85 | RAB9A (0.54) | MAPTRAB9AALDH1A1NPC1HPGD | |
| SCHEMBL27038532 | 0.85 | RAB9A (0.54) | MAPTRAB9AALDH1A1NPC1HPGD | |
| SCHEMBL169974 | 0.83 | MAPT (0.62) | MAPTRAB9AALDH1A1NPC1POLB | |
| SCHEMBL15434433 | 0.83 | MAPT (0.70) | MAPTRAB9AALDH1A1NPC1HPGD | |
| SCHEMBL10264622 | 0.83 | MAPT (0.49) | MAPTRAB9AALDH1A1NPC1HPGD | |
| SCHEMBL6844995 | 0.82 | MAPT (0.49) | MAPTRAB9AALDH1A1NPC1HPGD | |
| SCHEMBL30698449 | 0.82 | MAPT (0.49) | MAPTRAB9AALDH1A1NPC1HPGD | |
| SCHEMBL23320436 | 0.81 | RAB9A (0.54) | MAPTRAB9AALDH1A1NPC1HPGD | |
| SCHEMBL27037825 | 0.80 | GAA (0.66) | MAPTRAB9AALDH1A1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020156323-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2020-08-06 | — | — | WO | disclosed |