SCHEMBL22308372

SCHEMBL22308372

CC(C)N1CCN(C2CC2)C[C@@H]1C

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 13/20 0.39
CCR5 P51681 5/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22456379 1.00 CHRM2 (0.39) CHRM2CCR5
SCHEMBL7466487 0.87 CHRM2 (0.35) CHRM2CCR5
SCHEMBL23639564 0.82 CHRM2 (0.33) CHRM2CCR5
SCHEMBL20934999 0.82 CHRM2 (0.33) CHRM2CCR5
SCHEMBL25704420 0.82 CHRM2 (0.33) CHRM2CCR5
SCHEMBL25649712 0.77 HRH3 (0.36) CHRM2
SCHEMBL22456343 0.72 PARP1 (0.33) CHRM2CCR5
SCHEMBL24726452 0.72 PARP1 (0.33) CHRM2CCR5
SCHEMBL14818711 0.71 LMNA (0.32)
SCHEMBL12614467 0.71 LMNA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020156319-A1 N-FORMAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF 浙江海正药业股份有限公司 2020-08-06 WO disclosed