Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.58 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220421 | 0.91 | PDE4B (0.56) | PDE4BPDE7A | |
| SCHEMBL254775 | 0.88 | PDE4B (0.52) | PDE4B | |
| SCHEMBL222815 | 0.87 | PDE4B (0.72) | PDE4B | |
| SCHEMBL221173 | 0.86 | PDE4B (0.61) | PDE4BPDE3BPDE7APDE3A | |
| SCHEMBL13865612 | 0.85 | PDE4B (0.63) | PDE4BPDE3BPDE7APDE3A | |
| Hydrochloric Acid SCHEMBL2773651 | 0.85 | PDE4B (0.62) | PDE4BPDE3BPDE7APDE3A | |
| SCHEMBL8312183 | 0.84 | PDE4B (0.59) | PDE4BPDE3BPDE7APDE3A | |
| SCHEMBL583129 | 0.83 | PDE4B (0.74) | PDE4B | |
| SCHEMBL13870220 | 0.83 | PDE4B (0.58) | PDE4BPDE3BPDE7APDE3A | |
| SCHEMBL2774432 | 0.81 | PDE4B (0.56) | PDE4BPDE3BPDE7APDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004201-A1 | PHOSPHODIESTARASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004201-A1 | PHOSPHODIESTARASE INHIBITORS | PDE4A, PDE7A, PDE4B | PDE4B 3/4885PDE3B 10/4885PDE7A 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.