Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | PPM1B | O75688 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430039 | 0.89 | CYP1A2 (0.36) | CYP1A2HIF1AALDH1A1KMT2ABRD4 | |
| SCHEMBL22309984 | 0.88 | CYP1A2 (0.35) | CYP1A2HIF1AALDH1A1KMT2ABRD4 | |
| SCHEMBL30016667 | 0.81 | CYP1A2 (0.40) | CYP1A2HIF1AALDH1A1KMT2ABRD4 | |
| SCHEMBL22092594 | 0.79 | CYP1A2 (0.39) | CYP1A2HIF1AALDH1A1KMT2ABRD4 | |
| SCHEMBL11004912 | 0.79 | CYP1A2 (0.39) | CYP1A2HIF1AALDH1A1KMT2ABRD4 | |
| SCHEMBL29328848 | 0.78 | CYP1A2 (0.38) | CYP1A2HIF1AALDH1A1KMT2ABRD4 | |
| SCHEMBL29329319 | 0.75 | CYP1A2 (0.36) | CYP1A2HIF1AALDH1A1KMT2ABRD4 | |
| SCHEMBL29329317 | 0.75 | CYP1A2 (0.36) | CYP1A2HIF1AALDH1A1KMT2ABRD4 | |
| SCHEMBL3339309 | 0.73 | CYP1A2 (0.37) | CYP1A2HIF1AALDH1A1KMT2ABRD4 | |
| SCHEMBL3236730 | 0.73 | CYP1A2 (0.37) | CYP1A2HIF1AALDH1A1KMT2ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12331038-B2 | Hexone glucokinase inhibitor and use thereof | SHANDONG XUANZHU PHARMA CO., LTD. (CN) | 2025-06-17 | — | — | US | disclosed |
| CN-116023365-B | Ketohexokinase inhibitors and uses thereof | 轩竹生物科技股份有限公司 | 2025-02-14 | — | — | CN | disclosed |
| US-20240067633-A1 | KETOHEXOKINASE INHIBITOR AND USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2024-02-29 | — | — | US | disclosed |
| US-20240067633-A1 | KETOHEXOKINASE INHIBITOR AND USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2024-02-29 | — | — | US | disclosed |
| US-20240067633-A1 | KETOHEXOKINASE INHIBITOR AND USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2024-02-29 | — | — | US | disclosed |
| EP-4269404-A1 | KETOHEXOKINASE INHIBITOR AND USE THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-11-01 | — | — | EP | disclosed |
| US-20230271947-A1 | SALT AND CRYSTAL FORM OF KETOHEXOKINASE INHIBITOR AND USE THEREOF | Xuanzhu Biopharmaceutical Co., Ltd. (CN) | 2023-08-31 | — | — | US | disclosed |
| CN-116635377-A | Ketohexokinase inhibitors and uses thereof | 四川海思科制药有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-113999212-B | Salts, crystalline forms and uses of ketohexokinase inhibitors | 山东轩竹医药科技有限公司 | 2023-07-28 | — | — | CN | disclosed |
| EP-4190776-A1 | SALT AND CRYSTAL FORM OF KETOHEXOKINASE INHIBITOR AND USE THEREOF | Shandong Xuanzhu Pharma Co., Ltd. (CN) | 2023-06-07 | — | — | EP | disclosed |
| CN-113412260-B | Ketohexokinase inhibitors and uses thereof | 山东轩竹医药科技有限公司 | 2022-08-02 | — | — | CN | disclosed |
| WO-2022135390-A1 | KETOHEXOKINASE INHIBITOR AND USE THEREOF | 四川海思科制药有限公司 | 2022-06-30 | — | — | WO | disclosed |
| US-20220106299-A1 | HEXONE GLUCOKINASE INHIBITOR AND USE THEREOF | SHANDONG XUANZHU PHARMA CO., LTD. (CN) | 2022-04-07 | — | — | US | disclosed |
| WO-2022022476-A1 | SALT AND CRYSTAL FORM OF KETOHEXOKINASE INHIBITOR AND USE THEREOF | 山东轩竹医药科技有限公司 | 2022-02-03 | — | — | WO | disclosed |
| CN-113999212-A | Salts, crystalline forms and uses of ketohexokinase inhibitors | 山东轩竹医药科技有限公司 | 2022-02-01 | — | — | CN | disclosed |
| EP-3919484-A1 | HEXONE GLUCOKINASE INHIBITOR AND USE THEREOF | Shandong Xuanzhu Pharma Co., Ltd. (CN) | 2021-12-08 | — | — | EP | disclosed |
| EP-3919484-A1 | HEXONE GLUCOKINASE INHIBITOR AND USE THEREOF | Shandong Xuanzhu Pharma Co., Ltd. (CN) | 2021-12-08 | — | — | EP | disclosed |
| CN-113412260-A | Ketohexokinase inhibitors and uses thereof | 山东轩竹医药科技有限公司 | 2021-09-17 | — | — | CN | disclosed |
| WO-2020156445-A1 | HEXONE GLUCOKINASE INHIBITOR AND USE THEREOF | 山东轩竹医药科技有限公司 | 2020-08-06 | — | — | WO | disclosed |
| WO-2020156445-A1 | HEXONE GLUCOKINASE INHIBITOR AND USE THEREOF | 山东轩竹医药科技有限公司 | 2020-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271947-A1 | SALT AND CRYSTAL FORM OF KETOHEXOKINASE INHIBITOR AND USE THEREOF | KHK, HK1, HKDC1 | CYP1A2 2161/4885HIF1A 1221/4885ALDH1A1 1879/4885 |
| US-12331038-B2 | Hexone glucokinase inhibitor and use thereof | GCK, KHK, HK1 | CYP1A2 1259/4885HIF1A 721/4885ALDH1A1 1698/4885 |
| US-20220106299-A1 | HEXONE GLUCOKINASE INHIBITOR AND USE THEREOF | GCK, KHK, HK1 | CYP1A2 1259/4885HIF1A 721/4885ALDH1A1 1698/4885 |
| US-20240067633-A1 | KETOHEXOKINASE INHIBITOR AND USE THEREOF | KHK, GCK, HK1 | CYP1A2 606/4885HIF1A 584/4885ALDH1A1 710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.