Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL636729 | 0.99 | KMT2A (0.43) | KMT2AMEN1LMNATSHRALOX12 | |
| SCHEMBL636937 | 0.91 | TAAR1 (0.43) | KMT2AMEN1LMNATSHRALOX12 | |
| SCHEMBL917319 | 0.87 | MGLL (0.39) | KMT2AMEN1LMNATAAR1MGLL | |
| SCHEMBL641010 | 0.86 | MGLL (0.38) | KMT2AMEN1LMNATAAR1MGLL | |
| SCHEMBL637631 | 0.86 | MGLL (0.38) | KMT2AMEN1LMNATAAR1MGLL | |
| SCHEMBL636954 | 0.86 | MGLL (0.38) | KMT2AMEN1LMNATAAR1MGLL | |
| SCHEMBL637967 | 0.86 | MGLL (0.38) | KMT2AMEN1LMNATAAR1MGLL | |
| SCHEMBL637517 | 0.85 | MGLL (0.42) | KMT2AMGLLBCHELIPE | |
| SCHEMBL917276 | 0.85 | TAAR1 (0.45) | KMT2AMEN1LMNATSHRALOX12 | |
| SCHEMBL916906 | 0.83 | TAAR1 (0.43) | KMT2AMEN1LMNATSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2354120-A1 | Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof | XenoPort, Inc. (US) | 2011-08-10 | — | — | EP | disclosed |