Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | BMX | P51813 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20244095 | 0.95 | KDM4E (0.37) | KDM4EATML3MBTL1PTGER4MEN1 | |
| SCHEMBL17714909 | 0.95 | KDM4E (0.38) | KDM4EATML3MBTL1PTGER4MEN1 | |
| SCHEMBL17714915 | 0.95 | KDM4E (0.38) | KDM4EATML3MBTL1MEN1KMT2A | |
| SCHEMBL19039135 | 0.95 | KDM4E (0.40) | KDM4EATML3MBTL1MEN1KMT2A | |
| SCHEMBL17252435 | 0.95 | KDM4E (0.40) | KDM4EATML3MBTL1PTGER4MEN1 | |
| SCHEMBL21240902 | 0.94 | MEN1 (0.34) | KDM4EATML3MBTL1PTGER4MEN1 | |
| SCHEMBL21111160 | 0.94 | KDM4E (0.38) | KDM4EATML3MBTL1PTGER4MEN1 | |
| SCHEMBL26450920 | 0.94 | KDM4E (0.38) | KDM4EATML3MBTL1PTGER4MEN1 | |
| SCHEMBL17714833 | 0.94 | KDM4E (0.38) | KDM4EATML3MBTL1MEN1KMT2A | |
| SCHEMBL20803046 | 0.93 | MEN1 (0.34) | KDM4EATML3MBTL1PTGER4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200251660-A1 | MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES | MERCK PATENT GMBH (DE) | 2020-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200251660-A1 | MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES | DDT, ESD, ETFA | KDM4E 3065/4885ATM 4454/4885L3MBTL1 565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.