SCHEMBL22312

SCHEMBL22312

O=[N+]([O-])C(CO)(CO)CO

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
ALDH1A1 P00352 3/20 0.39
TSHR P16473 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
CA5A P35218 1/20 0.35
CA5B Q9Y2D0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28652710 1.00 LMNA (0.52) LMNAALDH1A1TSHRTDP1CA5A
Ammonia Solution, Strong SCHEMBL27791838 0.97 LMNA (0.50) LMNAALDH1A1TSHRTDP1CA5A
Potassium SCHEMBL8328705 0.97 LMNA (0.50) LMNAALDH1A1TSHRTDP1CA5A
Methane SCHEMBL1141018 0.97 LMNA (0.50) LMNAALDH1A1TSHRTDP1CA5A
Nitric Acid SCHEMBL29219452 0.94 LMNA (0.48) LMNAALDH1A1TSHRTDP1CA5A
SCHEMBL27375341 0.94 LMNA (0.48) LMNAALDH1A1TSHRTDP1CA5A
Ammonia Solution, Strong SCHEMBL27816712 0.94 LMNA (0.48) LMNAALDH1A1TSHRTDP1CA5A
Fluoromethane SCHEMBL27452229 0.91 LMNA (0.46) LMNAALDH1A1TSHRTDP1CA5A
Alcohol SCHEMBL27715966 0.91 LMNA (0.46) LMNAALDH1A1TSHRTDP1CA5A
SCHEMBL8351999 0.90 LMNA (0.50) LMNAALDH1A1TSHRTDP1CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2801 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4723138-A1 ELECTRICALLY CONDUCTIVE COMPOSITION Henkel AG & Co. KGaA (DE) 2026-04-08 EP claimed
US-20260078296-A1 SUSTAINED-RELEASE SCALE INHIBITORS Materials Engineering and Technical Support Services (US) 2026-03-19 US claimed
EP-4680201-A1 COMPOSITIONS AND USES THEREOF FOR STABILIZATION OF BLOOD SAMPLE COMPONENTS Streck LLC (US) 2026-01-21 EP claimed
EP-3614839-B1 STABLE BIOCIDAL COMPOSITIONS LANXESS CORP (US) 2026-01-07 EP claimed
US-20250195341-A1 Personal Care Compositions Incorporating Natural Benefit Agents And Methods For The Same COLGATE-PALMOLIVE COMPANY (US) 2025-06-19 US claimed
CN-120040305-A Method for preparing tris (hydroxymethyl) aminomethane by trickle bed process 北京旭阳科技有限公司 2025-05-27 CN claimed
EP-3836889-B1 SOLID CLEANSING COMPOSTIONS AND METHODS FOR THE SAME COLGATE PALMOLIVE CO (US) 2025-05-14 EP claimed
EP-4549619-A1 PREPARATION OF AMINES BY HYDROGENATION OF NITRO COMPOUNDS USING HYDROGEN WITH LOW DEUTERIUM CONTENT BASF SE (DE) 2025-05-07 EP claimed
CN-119841736-A Method for synthesizing tris (hydroxymethyl) aminomethane 湖北远大富驰医药化工股份有限公司 2025-04-18 CN claimed
CN-115872875-B Preparation method of tris (hydroxymethyl) aminomethane 湖北远大富驰医药化工股份有限公司 2025-04-15 CN claimed
US-4298638-A TOUGHNESS, WATER RESISTANCE INTERNATIONAL MINERALS & CHEMICAL CORP. (US) 1981-11-03 US claimed
US-4243800-A Strippable coating resin from nitroalkanol and polyamine INTERNATIONAL MINERALS & CHEMICAL CORP. (US) 1981-01-06 US claimed
US-4219631-A WITH A NITROALKANOL; TREATING TEXTILES AND NON-WOVEN CELLULOSIC PRODUCTS TO PROVIDE WRINKLE RESISTANCE, PERMANENT PRESS INTERNATIONAL MINERALS & CHEMICAL CORP. (US) 1980-08-26 US claimed
US-4194063-A ENZYMATIC DECOMPOSITION TO AMMONIA WHICH REACTS WITH A BETA-DIKETONE AND FORMALDEHYDE TO FORM A DIHYDROPYRIDINE EASTMAN KODAK COMPANY (US) 1980-03-18 US claimed
EP-0004217-A1 Process for the bactericidal and biostatical treatment of a polluted medium SOCIETE CHIMIQUE DE LA GRANDE PAROISSE, AZOTE ET PRODUITS CHIMIQUES (FR) 1979-09-19 EP claimed
US-4101433-A TRIS/HYDROXYMETHYL/NITROMETHANE, NITROMORPHOLINE COMPOUND, MICROBIOCIDE IMC CHEMICAL GROUP, INC. (US) 1978-07-18 US claimed
US-4039495-A Water-dispersed coating composition of short oil alkyd resin and tris(hydroxymethyl)nitromethane IMC CHEMICAL GROUP, INC. (US) 1977-08-02 US claimed
US-4008332-A 2-HYDROXYMETHYL-2-NITRO-1,3-PROPANEDIOL THOMAS RICHARD DEAN 1977-02-15 US claimed
US-3982993-A Preparation of a wax containing paper sheet GEORGIA-PACIFIC CORPORATION (US) 1976-09-28 US claimed
US-3973971-A REACTION WITH FORMALDEHYDE, NITRO COMPOUND OR ALUMINUM, ZINC, OR SULFUR KOPPERS COMPANY, INC. (US) 1976-08-10 US claimed