Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 9/20 | 0.45 |
| ▸ | GRM3 | Q14832 | 6/20 | 0.45 |
| ▸ | GRM6 | O15303 | 6/20 | 0.45 |
| ▸ | GRM8 | O00222 | 4/20 | 0.45 |
| ▸ | ARG1 | P05089 | 3/20 | 0.38 |
| ▸ | ARG2 | P78540 | 2/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2788379 | 1.00 | GRM2 (0.45) | GRM2GRM3GRM6GRM8ARG1 | |
| SCHEMBL2231253 | 1.00 | GRM2 (0.45) | GRM2GRM3GRM6GRM8ARG1 | |
| SCHEMBL678446 | 1.00 | GRM2 (0.45) | GRM2GRM3GRM6GRM8ARG1 | |
| SCHEMBL2230041 | 1.00 | GRM2 (0.45) | GRM2GRM3GRM6GRM8ARG1 | |
| SCHEMBL13319983 | 0.74 | GRM2 (0.53) | GRM2GRM3GRM6GRM8GRM1 | |
| SCHEMBL20543419 | 0.74 | GRM6 (0.41) | GRM2GRM3GRM6GRM8ARG1 | |
| SCHEMBL15062900 | 0.73 | ARG1 (0.42) | GRM2GRM3GRM6GRM8ARG1 | |
| SCHEMBL28686657 | 0.73 | ARG1 (0.42) | GRM2GRM3GRM6GRM8ARG1 | |
| SCHEMBL8438555 | 0.71 | GRM2 (0.40) | GRM2GRM3GRM6GRM8ARG1 | |
| SCHEMBL8442848 | 0.71 | GRM2 (0.40) | GRM2GRM3GRM6GRM8ARG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091033-A1 | MODULATION OF NEUROGENESIS BY PPAR AGENTS | BRAINCELLS, INC. (US) | 2011-07-28 | — | — | WO | disclosed |