Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16877684 | 0.91 | MBTD1 (0.34) | MBTD1L3MBTL3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23682807 | 0.86 | MBTD1 (0.40) | MBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL4073795 | 0.83 | MBTD1 (0.34) | MBTD1L3MBTL3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14760006 | 0.83 | MBTD1 (0.31) | MBTD1L3MBTL3 | |
| SCHEMBL15706823 | 0.83 | EPAS1 (0.32) | MBTD1L3MBTL3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16878115 | 0.83 | EPAS1 (0.32) | MBTD1L3MBTL3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16877787 | 0.83 | MBTD1 (0.31) | MBTD1L3MBTL3 | |
| SCHEMBL4075621 | 0.82 | — | — | |
| SCHEMBL16877471 | 0.77 | — | — | |
| SCHEMBL10731648 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160109-A1 | DIHYDRONAPHTHYRIDINONE COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 劲方医药科技(上海)有限公司 | 2021-08-19 | — | — | WO | disclosed |
| WO-2021083167-A1 | SUBSTITUTED HETEROCYCLIC FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 劲方医药科技(上海)有限公司 | 2021-05-06 | — | — | WO | disclosed |
| WO-2020156311-A1 | PYRIDAZINE DERIVATIVE INHIBITOR, AND PREPARATION METHOD AND APPLICATION THEREOF | 江苏豪森药业集团有限公司 | 2020-08-06 | — | — | WO | disclosed |