Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 5/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.46 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23052026 | 0.84 | CYP2D6 (0.54) | ALDH1A1L3MBTL1KMT2ADPP4DPP7 | |
| SCHEMBL2372258 | 0.83 | HDAC8 (0.57) | ALDH1A1L3MBTL1KMT2ATDP1CNR1 | |
| SCHEMBL2192672 | 0.80 | ALOX5AP (0.57) | ALDH1A1L3MBTL1DPP4DPP7KCNH2 | |
| SCHEMBL2192669 | 0.80 | ALOX5AP (0.57) | ALDH1A1L3MBTL1DPP4DPP7KCNH2 | |
| SCHEMBL6871162 | 0.78 | KMT5B (0.57) | ALDH1A1L3MBTL1HPGDKMT2ATDP1 | |
| SCHEMBL6871158 | 0.78 | KMT5B (0.57) | ALDH1A1L3MBTL1HPGDKMT2ATDP1 | |
| SCHEMBL1020188 | 0.77 | DPP4 (0.46) | L3MBTL1KMT2ATDP1DPP4DPP7 | |
| SCHEMBL3528220 | 0.77 | HDAC8 (0.52) | ALDH1A1L3MBTL1TDP1CNR2HDAC8 | |
| SCHEMBL3524394 | 0.77 | DPP4 (0.52) | HPGDKMT2ATDP1DPP4DPP7 | |
| SCHEMBL1767735 | 0.76 | CA1 (0.50) | KMT2AEPHX2ACLYCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200247761-A1 | SULFONAMIDE OR AMIDE COMPOUNDS, COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND/OR TREATMENT OF AUTOIMMUNE, INFLAMMATION OR INFECTION RELATED DISORDERS | TAIWANJ PHARMACEUTICALS CO., LTD (TW) | 2020-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200247761-A1 | SULFONAMIDE OR AMIDE COMPOUNDS, COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND/OR TREATMENT OF AUTOIMMUNE, INFLAMMATION OR INFECTION RELATED DISORDERS | TLR4, TLR1, TLR5 | ALDH1A1 3965/4885L3MBTL1 4745/4885HPGD 4306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.