SCHEMBL22315719

SCHEMBL22315719

N#Cc1ccc2c(c1)oc1c(Cl)cccc12

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ IDO1 P14902 2/20 0.50
▸ AHR P35869 7/20 0.47
▸ TTR P02766 3/20 0.45
▸ PSMB8 P28062 1/20 0.43
▸ PSMB5 P28074 1/20 0.43
▸ PIM1 P11309 1/20 0.41
▸ CSNK2A2 P19784 1/20 0.41
▸ CSNK2B P67870 1/20 0.41
▸ PIM3 Q86V86 1/20 0.41
▸ PIM2 Q9P1W9 1/20 0.41
▸ TDO2 P48775 1/20 0.38
▸ CA1 P00915 2/20 0.38
▸ CA2 P00918 2/20 0.38
▸ DYRK1A Q13627 1/20 0.36
▸ TNKS O95271 1/20 0.35
▸ SLC6A4 P31645 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31672685 1.00 IDO1 (0.50) IDO1AHRTTRPSMB8PSMB5
SCHEMBL31355175 0.97 IDO1 (0.48) IDO1AHRTTRPSMB8PSMB5
SCHEMBL22284813 0.88 PIM1 (0.49) IDO1AHRTTRPSMB8PSMB5
SCHEMBL13564568 0.83 IDO1 (0.42) IDO1AHRPIM1CSNK2A2CSNK2B
SCHEMBL29623029 0.81 IDO1 (0.40) IDO1TDO2CA1CA2DYRK1A
SCHEMBL18347519 0.81 IDO1 (0.46) IDO1TDO2CA1CA2DYRK1A
SCHEMBL29693277 0.79 IDO1 (0.51) IDO1AHRTTRPIM1CSNK2A2
SCHEMBL548396 0.77 IDO1 (0.45) IDO1AHRTDO2CA1CA2
SCHEMBL3086890 0.76 AHR (0.53) IDO1AHRTDO2CA1CA2
SCHEMBL22117396 0.76 AHR (0.51) AHRTTRPIM1CSNK2A2CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773399-B Metal organic luminescent material and application thereof 北京云基科技股份有限公司 2024-06-14 — — CN disclosed
US-11785839-B2 Organic light-emitting materials containing cyano-substituted ligand Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-10-10 — — US disclosed
US-11785839-B2 Organic light-emitting materials containing cyano-substituted ligand Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-10-10 — — US disclosed
US-20230312627-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-10-05 — — US disclosed
US-20230312627-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-10-05 — — US disclosed
CN-116535443-A Organic electroluminescent material and device thereof 北京夏禾科技有限公司 2023-08-04 — — CN disclosed
US-20230240129-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-27 — — US disclosed
US-20230240129-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-27 — — US disclosed
US-20230240129-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-27 — — US disclosed
CN-115873591-A Phosphorescent organic electroluminescent material and luminescent device 北京云基科技有限公司 2023-03-31 — — CN disclosed
CN-114773399-A Metal organic luminescent material and application thereof 北京云基科技有限公司 2022-07-22 — — CN disclosed
US-20200251666-A1 ORGANIC LIGHT-EMITTING MATERIALS CONTAINING CYANO-SUBSTITUTED LIGAND Beijing Summer Sprout Technology Co., Ltd. (CN) 2020-08-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200251666-A1 ORGANIC LIGHT-EMITTING MATERIALS CONTAINING CYANO-SUBSTITUTED LIGAND L1CAM, CYBA, ICOSLG IDO1 2002/4885AHR 2485/4885TTR 1549/4885
US-20230312627-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF LEF1, CTCF, DNMT1 IDO1 2520/4885AHR 1358/4885TTR 3926/4885
US-11785839-B2 Organic light-emitting materials containing cyano-substituted ligand L1CAM, CYBA, ICOSLG IDO1 2002/4885AHR 2485/4885TTR 1549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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