Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 10/20 | 0.80 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.80 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | ESR1 | P03372 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.66 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.66 |
| ▸ | SHBG | P04278 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | PGR | P06401 | 1/20 | 0.66 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | AR | P10275 | 1/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.66 |
| ▸ | SNCA | P37840 | 1/20 | 0.66 |
| ▸ | HTR2B | P41595 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13123039 | 1.00 | STS (0.80) | STSCYP19A1HSD17B1LMNAESR1 | |
| Sulfuric Acid SCHEMBL21408951 | 0.95 | STS (0.74) | STSCYP19A1HSD17B1LMNAESR1 | |
| SCHEMBL978711 | 0.90 | STS (0.77) | STSCYP19A1HSD17B1LMNAESR1 | |
| SCHEMBL13930486 | 0.89 | STS (1.00) | STSCYP19A1HSD17B1LMNAESR1 | |
| SCHEMBL10889130 | 0.89 | CYP19A1 (1.00) | STSCYP19A1HSD17B1LMNAESR1 | |
| SCHEMBL14048663 | 0.89 | STS (0.75) | STSCYP19A1HSD17B1LMNAESR1 | |
| SCHEMBL2929474 | 0.89 | STS (1.00) | STSCYP19A1HSD17B1LMNAESR1 | |
| SCHEMBL1705295 | 0.89 | STS (0.75) | STSCYP19A1HSD17B1LMNAESR1 | |
| SCHEMBL10783004 | 0.89 | STS (0.75) | STSCYP19A1HSD17B1LMNAESR1 | |
| SCHEMBL13930484 | 0.89 | STS (0.75) | STSCYP19A1HSD17B1LMNAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 485 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024259428-A2 | ESTROGENIC COMPOUNDS AND FORMULATIONS FOR GESTATION-RELATED COMPLICATIONS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2024-12-19 | — | — | WO | claimed |
| CN-118858479-A | Kit for simultaneously detecting 90 steroid hormones and metabolites thereof in urine sample, detection method and sample pretreatment method | 中国疾病预防控制中心环境与健康相关产品安全所 | 2024-10-29 | — | — | CN | claimed |
| CN-118425368-A | High performance liquid chromatography tandem mass spectrometry detection method for 6 estrogens and metabolites thereof in human urine | 海南一龄医疗产业发展有限公司 | 2024-08-02 | — | — | CN | claimed |
| US-20240093191-A1 | COMPOSITIONS AND METHODS FOR TREATING DISEASE ASSOCIATED WITH DUX4 OVEREXPRESSION | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (US) | 2024-03-21 | — | — | US | claimed |
| EP-4288539-A1 | COMPOSITIONS AND METHODS FOR TREATING DISEASE ASSOCIATED WITH DUX4 OVEREXPRESSION | Research Institute at Nationwide Children's Hospital (US) | 2023-12-13 | — | — | EP | claimed |
| WO-2023234790-A1 | APPLICATION OF HYDROGEN PEROXIDE AND 17β-ESTRADIOL AND ITS METABOLITES AS BIOMARKERS IN A METHOD OF DIAGNOSING NEURODEGENERATIVE DISEASES IN VITRO | GDANSKI UNIWERSYTET MEDYCZNY (PL) | 2023-12-07 | — | — | WO | claimed |
| CN-116286890-A | Three-component oxidation system and application thereof in degradation of 4-hydroxy estrone | 安徽大学 | 2023-06-23 | — | — | CN | claimed |
| WO-2022169922-A1 | COMPOSITIONS AND METHODS FOR TREATING DISEASE ASSOCIATED WITH DUX4 OVEREXPRESSION | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (US) | 2022-08-11 | — | — | WO | claimed |
| WO-2022082183-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF INFLAMMATORY AND METABOLIC DISEASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | claimed |
| CN-113552264-A | High performance liquid chromatography tandem mass spectrometry detection method for 6 estrogens and metabolites thereof in human urine | 海南一龄医疗产业发展有限公司 | 2021-10-26 | — | — | CN | claimed |
| WO-2003013536-A9 | METHODS FOR TREATMENT OF CANCER USING IRINOTECAN BASED ON UGT1A1 | EPIDAUROS BIOTECHNOLOGIE AG (DE) | 2004-04-29 | — | — | WO | claimed |
| EP-1408974-A2 | METHODS FOR TREATMENT OF CANCER USING IRINOTECAN BASED ON UGT1A1 | Epidauros Biotechnologie AG (DE) | 2004-04-21 | — | — | EP | claimed |
| US-20030099960-A1 | Administration of epirubicin for use in the treatment of cancer; obtain sample, incubate with antitumor agent, monitor adjustment in glucoronyltransferase activity, evaluate effectiveness antitumor agent | THE UNIVERSITY OF CHICAGO | 2003-05-29 | — | — | US | claimed |
| WO-2003013536-A2 | METHODS FOR TREATMENT OF CANCER USING IRINOTECAN BASED ON UGT1A1 | EPIDAUROS BIOTECHNOLOGIE AG (DE) | 2003-02-20 | — | — | WO | claimed |
| WO-2002059375-A9 | DETERMINATION OF UGT2B7 GENE POLYMORPHISMS FOR PREDICTING UGT2B7 SUBSTRATE TOXICITY AND FOR OPTIMISING DRUG DOSAGE | UNIV CHICAGO (US) | 2002-10-31 | — | — | WO | claimed |
| WO-2002059375-A2 | DETERMINATION OF UGT2B7 GENE POLYMORPHISMS FOR PREDICTING UGT2B7 SUBSTRATE TOXICITY AND FOR OPTIMISING DRUG DOSAGE | UNIVERSITY OF CHICAGO (US) | 2002-08-01 | — | — | WO | claimed |
| EP-0409176-B1 | Method and materials for detecting pathology from alterations in estrogen metabolism | UNIV ROCKEFELLER (US) | 1999-04-28 | — | — | EP | claimed |
| EP-0866969-A1 | METHOD OF CANCER DETECTION | IMMUNA CARE CORPORATION (US) | 1998-09-30 | — | — | EP | claimed |
| WO-1997011374-A1 | METHOD OF CANCER DETECTION | IMMUNA CARE CORPORATION (US) | 1997-03-27 | — | — | WO | claimed |
| EP-0409176-A2 | Method and materials for detecting pathology from alterations in estrogen metabolism | THE ROCKEFELLER UNIVERSITY (US) | 1991-01-23 | — | — | EP | claimed |