Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 10/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.75 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.62 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
| ▸ | SHBG | P04278 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | PGR | P06401 | 1/20 | 0.62 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | AR | P10275 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.62 |
| ▸ | SNCA | P37840 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13930486 | 1.00 | STS (1.00) | STSCYP19A1HSD17B1AKR1B10LMNA | |
| SCHEMBL13123039 | 0.89 | STS (0.80) | STSCYP19A1HSD17B1AKR1B10LMNA | |
| SCHEMBL223170 | 0.89 | STS (0.80) | STSCYP19A1HSD17B1AKR1B10LMNA | |
| SCHEMBL978711 | 0.87 | STS (0.77) | STSCYP19A1HSD17B1AKR1B10LMNA | |
| SCHEMBL1705295 | 0.86 | STS (0.75) | STSCYP19A1HSD17B1AKR1B10LMNA | |
| SCHEMBL10889130 | 0.86 | CYP19A1 (1.00) | STSCYP19A1HSD17B1AKR1B10LMNA | |
| SCHEMBL14048663 | 0.86 | STS (0.75) | STSCYP19A1HSD17B1AKR1B10LMNA | |
| SCHEMBL10783004 | 0.86 | STS (0.75) | STSCYP19A1HSD17B1AKR1B10LMNA | |
| SCHEMBL13930484 | 0.86 | STS (0.75) | STSCYP19A1HSD17B1AKR1B10LMNA | |
| SCHEMBL7932972 | 0.85 | STS (0.74) | STSCYP19A1HSD17B1AKR1B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773136-B | Method for synthesizing aromatic amine | 陕西师范大学 | 2023-06-16 | — | — | CN | disclosed |
| CN-114773136-A | Method for synthesizing arylamine | 陕西师范大学 | 2022-07-22 | — | — | CN | disclosed |
| US-9284345-B2 | 17alpha-substituted steroids as systemic antiandrogens and selective androgen receptor modulators | ENDORECHERCHE, INC. (CA) | 2016-03-15 | — | — | US | disclosed |
| EP-2147014-B1 | 17ALPHA-SUBSTITUTED STEROIDS AS SYSTEMIC ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS | ENDORECH INC (CA) | 2016-02-17 | — | — | EP | disclosed |
| EP-2147014-A1 | 17ALPHA-SUBSTITUTED STEROIDS AS SYSTEMIC ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS | Endorecherche, Inc. (CA) | 2010-01-27 | — | — | EP | disclosed |
| US-20090042844-A1 | 17ALPHA-SUBSTITUTED STEROIDS AS SYSTEMIC ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS | ENDORECHERCHE, INC. | 2009-02-12 | — | — | US | disclosed |
| WO-2008124922-A1 | 17ALPHA-SUBSTITUTED STEROIDS AS SYSTEMIC ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS | ENDORECHERCHE, INC. (CA) | 2008-10-23 | — | — | WO | disclosed |
| US-20070087383-A1 | Immunoassay | THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED (NZ) | 2007-04-19 | — | — | US | disclosed |
| EP-1668345-A1 | IMMUNOASSAY | The Horticulture and Food Research Institute of New Zealand Limited (NZ) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005026702-A1 | IMMUNOASSAY | THE HORTICULTURE AND FOOD RESEARCH INSTITUTE OF NEW ZEALAND LIMITED (NZ) | 2005-03-24 | — | — | WO | disclosed |
| US-20040224935-A1 | Topical antiandrogenic steroids | ENDORECHERCHE, INC. | 2004-11-11 | — | — | US | disclosed |
| WO-2004089971-A1 | TOPICAL ANTIANDROGENIC STEROIDS | ENDORECHERCHE, INC. (CA) | 2004-10-21 | — | — | WO | disclosed |
| EP-0946583-A1 | BISSTEROIDAL COMPOUNDS AND THEIR USE FOR THE PREPARATION OF CHIRAL COMPLEXES | Schering Aktiengesellschaft (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028322-A1 | BISSTEROIDAL COMPOUNDS AND THEIR USE FOR THE PREPARATION OF CHIRAL COMPLEXES | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-07-02 | — | — | WO | disclosed |
| EP-0849274-A1 | Bissteroidal compounds and their use for the preparation of chiral complexes | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-06-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042844-A1 | 17ALPHA-SUBSTITUTED STEROIDS AS SYSTEMIC ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS | AR, NR5A1, SRD5A1 | STS 142/4885CYP19A1 8/4885HSD17B1 10/4885 |
| US-20040224935-A1 | Topical antiandrogenic steroids | CYP17A1, SRD5A1, SRD5A2 | STS 55/4885CYP19A1 16/4885HSD17B1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.