Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76577 | 0.96 | PAOX (0.57) | PAOXHPGDDUSP3ALDH1A1CYP2C19 | |
| SCHEMBL721355 | 0.88 | PAOX (0.64) | PAOXHPGDDUSP3ALDH1A1CYP2C19 | |
| SCHEMBL2238005 | 0.87 | PAOX (0.59) | PAOXHPGDDUSP3ALDH1A1CYP2C19 | |
| SCHEMBL3200520 | 0.87 | PAOX (0.59) | PAOXHPGDDUSP3ALDH1A1CYP2C19 | |
| Hydrochloric Acid SCHEMBL2488967 | 0.86 | PAOX (0.62) | PAOXHPGDDUSP3ALDH1A1CYP2C19 | |
| SCHEMBL540786 | 0.85 | PAOX (0.62) | PAOXHPGDDUSP3ALDH1A1CYP2C19 | |
| SCHEMBL39800 | 0.84 | CA12 (0.47) | PAOXHPGDDUSP3ALDH1A1CYP2D6 | |
| SCHEMBL20966331 | 0.84 | PAOX (0.65) | PAOXHPGDDUSP3ALDH1A1CYP2C19 | |
| SCHEMBL169004 | 0.84 | PAOX (0.65) | PAOXHPGDDUSP3ALDH1A1CYP2C19 | |
| SCHEMBL4398803 | 0.82 | PAOX (0.62) | PAOXHPGDDUSP3ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160174-A1 | USES OF COMPOUNDS HAVING ANTI-HSV-1 ACTIVITY | UNIVERSITA DEGLI STUDI DI PADOVA (IT) | 2020-08-06 | — | — | WO | disclosed |