Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22317835 | 0.96 | PAOX (0.58) | PAOXHPGDDUSP3ALDH1A1CYP2C19 | |
| SCHEMBL39800 | 0.88 | CA12 (0.47) | PAOXHPGDDUSP3ALDH1A1CYP2D6 | |
| SCHEMBL721355 | 0.87 | PAOX (0.64) | PAOXHPGDDUSP3ALDH1A1CYP2C19 | |
| SCHEMBL2238005 | 0.86 | PAOX (0.59) | PAOXHPGDDUSP3ALDH1A1CYP2C19 | |
| SCHEMBL3200520 | 0.86 | PAOX (0.59) | PAOXHPGDDUSP3ALDH1A1CYP2C19 | |
| Hydrochloric Acid SCHEMBL2488967 | 0.85 | PAOX (0.62) | PAOXHPGDDUSP3ALDH1A1CYP2C19 | |
| SCHEMBL4640495 | 0.85 | CYP2C19 (0.50) | PAOXCYP2C19SMN1; SMN2KDM1ACYP1A2 | |
| SCHEMBL21572857 | 0.85 | — | — | |
| SCHEMBL540786 | 0.85 | PAOX (0.62) | PAOXHPGDDUSP3ALDH1A1CYP2C19 | |
| SCHEMBL169004 | 0.83 | PAOX (0.65) | PAOXHPGDDUSP3ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119751380-A | Polyamine heterocyclic compound, preparation method and application thereof, and polyamine heterocyclic compound combined solution | 大连理工大学 | 2025-04-04 | — | — | CN | disclosed |
| US-20230399303-A1 | Macrophage Migration Inhibitory Factor Inhibitors, and Methods of Making and Using Same | UNIV YALE (US) | 2023-12-14 | — | — | US | disclosed |
| WO-2023220425-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023150618-A2 | CONJUGATED HEPCIDIN MIMETICS | PROTAGONIST THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |
| US-20230174485-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230056729-A1 | REPLICATION PROTEIN A (RPA)-DNA INTERACTION INHIBITORS | NATIONAL INSTITUTES OF HEALTH | 2023-02-23 | — | — | US | disclosed |
| US-11370794-B2 | Toll-like receptor antagonist compounds and methods of use | DYNAVAX TECHNOLOGIES CORPORATION (US) | 2022-06-28 | — | — | US | disclosed |
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |
| WO-2021101919-A1 | COMPOUNDS USEFUL AS INHIBITORS OF HELIOS PROTEIN | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-05-27 | — | — | WO | disclosed |
| US-10968198-B2 | Biaryltriazole inhibitors of macrophage migration inhibitory factor | YALE UNIVERSITY (US) | 2021-04-06 | — | — | US | disclosed |
| US-20070099924-A1 | Aminobenzimidazoles and benzimidazoles as inhibitors of respiratory syncytial virus replication | JANSSEN SCIENCES IRELAND UC (IE) | 2007-05-03 | — | — | US | disclosed |
| WO-2007025009-A2 | INDENOISOQUINOLINONE ANALOGS AND METHODS OF USE THEREOF | INOTEK PHARMACEUTICALS CORPORATION (US) | 2007-03-01 | — | — | WO | disclosed |
| US-20070049555-A1 | Indenoisoquinolinone analogs and methods of use thereof | INOTEK PHARMACEUTICALS CORPORATION (US) | 2007-03-01 | — | — | US | disclosed |
| US-20070049555-A1 | Indenoisoquinolinone analogs and methods of use thereof | INOTEK PHARMACEUTICALS CORPORATION (US) | 2007-03-01 | — | — | US | disclosed |
| US-20070032490-A1 | N-Phenyl-'(4-pyridyl)-azinyl!amine derivatives as plant protection agents | SYNGENTA CROP PROTECTION, INC. | 2007-02-08 | — | — | US | disclosed |
| WO-2005058869-A1 | AMINOBENZIMIDAZOLES AND BENZIMIDAZOLES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-06-30 | — | — | WO | disclosed |
| EP-1290056-A1 | POLYURETHANE COMPOSITIONS BASED ON POLYESTER BLOCK COPOLYMERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-03-12 | — | — | EP | disclosed |
| EP-1250394-A1 | POLYURETHANE COMPOSITIONS ON THE BASIS OF POLYESTER-POLYETHER COPOLYMERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001096436-A1 | POLYURETHANE COMPOSITIONS BASED ON POLYESTER BLOCK COPOLYMERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-12-20 | — | — | WO | disclosed |
| WO-2001046330-A1 | POLYURETHANE COMPOSITIONS ON THE BASIS OF POLYESTER-POLYETHER COPOLYMERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099924-A1 | Aminobenzimidazoles and benzimidazoles as inhibitors of respiratory syncytial virus replication | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, H1-2, H1-4 | PAOX 2041/4885HPGD 2408/4885DUSP3 4589/4885 |
| US-10968198-B2 | Biaryltriazole inhibitors of macrophage migration inhibitory factor | MIF, MMP12, CSF1R | PAOX 1249/4885HPGD 2926/4885DUSP3 1891/4885 |
| US-20070049555-A1 | Indenoisoquinolinone analogs and methods of use thereof | TNNI3, IDH2, GLS | PAOX 2291/4885HPGD 178/4885DUSP3 2850/4885 |
| US-20070032490-A1 | N-Phenyl-'(4-pyridyl)-azinyl!amine derivatives as plant protection agents | CYP1A1, NAT1, AKR7A2 | PAOX 57/4885HPGD 2639/4885DUSP3 3831/4885 |
| US-11370794-B2 | Toll-like receptor antagonist compounds and methods of use | TLR9, TLR7, TLR8 | PAOX 1763/4885HPGD 3971/4885DUSP3 1806/4885 |
| US-20230056729-A1 | REPLICATION PROTEIN A (RPA)-DNA INTERACTION INHIBITORS | RPA1, RPA3, RPAP1 | PAOX 1986/4885HPGD 2345/4885DUSP3 2560/4885 |
| US-20230174485-A1 | LIPOXYGENASE INHIBITORS | ALOX15B, ALOX12, ALOX15 | PAOX 158/4885HPGD 28/4885DUSP3 2736/4885 |
| US-20230399303-A1 | Macrophage Migration Inhibitory Factor Inhibitors, and Methods of Making and Using Same | MIF, MMP12, METAP1 | PAOX 3639/4885HPGD 1425/4885DUSP3 1021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.