Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13751271 | 0.86 | ALDH1A1 (0.35) | SMN1; SMN2 | |
| SCHEMBL13751274 | 0.84 | CYP2D6 (0.34) | — | |
| SCHEMBL22301662 | 0.81 | CHRM2 (0.30) | — | |
| SCHEMBL27072955 | 0.81 | — | — | |
| SCHEMBL13751280 | 0.80 | ALDH1A1 (0.37) | SMN1; SMN2 | |
| SCHEMBL25089471 | 0.79 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL27281048 | 0.79 | — | — | |
| SCHEMBL27280968 | 0.79 | — | — | |
| SCHEMBL22952346 | 0.78 | CHRM2 (0.31) | — | |
| SCHEMBL24338026 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160198-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |