Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | ACACA | Q13085 | 2/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231836 | 1.00 | MAOB (0.41) | MAOBMAOANR4A2KMT2AMEN1 | |
| SCHEMBL2234783 | 0.89 | MAOB (0.47) | MAOBMAOANR4A2KMT2AMEN1 | |
| SCHEMBL2234792 | 0.89 | MAOB (0.47) | MAOBMAOANR4A2KMT2AMEN1 | |
| SCHEMBL2234795 | 0.89 | MAOB (0.47) | MAOBMAOANR4A2KMT2AMEN1 | |
| SCHEMBL2233197 | 0.87 | MAOB (0.38) | MAOBFFAR1FFAR4ALOX5ALOX5AP | |
| SCHEMBL2233202 | 0.87 | MAOB (0.38) | MAOBFFAR1FFAR4ALOX5ALOX5AP | |
| SCHEMBL16161742 | 0.83 | KDM4E (0.32) | POLBACACBTHRATHRB | |
| SCHEMBL2231831 | 0.83 | KMT2A (0.41) | MAOBMAOANR4A2KMT2AMEN1 | |
| SCHEMBL2235743 | 0.82 | MAOB (0.43) | MAOBMAOANR4A2KMT2AMEN1 | |
| SCHEMBL2235734 | 0.82 | MAOB (0.43) | MAOBMAOANR4A2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011093524-A1 | DI - SUBSTITUTED PYRIDINE DERIVATIVES AS ANTICANCERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-08-04 | — | — | WO | disclosed |