Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | PNMT | P11086 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21196889 | 0.86 | TSHR (0.41) | TSHRALDH1A1NPC1TP53NFKB1 | |
| SCHEMBL3889788 | 0.83 | TSHR (0.42) | TSHRALDH1A1NPC1TP53NFKB1 | |
| SCHEMBL9486124 | 0.83 | TSHR (0.42) | TSHRALDH1A1NPC1TP53NFKB1 | |
| SCHEMBL19739521 | 0.81 | KMT2A (0.35) | ALDH1A1NPC1TP53RAB9APTGS1 | |
| SCHEMBL17966523 | 0.80 | TSHR (0.44) | TSHRALDH1A1NPC1TP53NFKB1 | |
| SCHEMBL2335006 | 0.80 | TSHR (0.44) | TSHRALDH1A1NPC1TP53NFKB1 | |
| SCHEMBL17966510 | 0.80 | TSHR (0.44) | TSHRALDH1A1NPC1TP53NFKB1 | |
| SCHEMBL31465211 | 0.80 | TSHR (0.44) | TSHRALDH1A1NPC1TP53NFKB1 | |
| SCHEMBL23532361 | 0.77 | TSHR (0.46) | TSHRALDH1A1NPC1TP53NFKB1 | |
| SCHEMBL11771061 | 0.76 | MEN1 (0.38) | TSHRALDH1A1PNMTTAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3253771-B1 | METHOD OF PRODUCING ORGANOHALOSILANES | DOW SILICONES CORP (US) | 2020-08-12 | — | — | EP | disclosed |