SCHEMBL22319081

SCHEMBL22319081

CCC(C)[SiH](C(C)CC)C(C)(C)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.38
HIF1A Q16665 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
GRIN1 Q05586 5/20 0.37
GRIN2A Q12879 5/20 0.37
GRIN2D O15399 4/20 0.37
GRIN2C Q14957 4/20 0.37
GRIN2B Q13224 3/20 0.37
KCNN4 O15554 1/20 0.36
MAPK1 P28482 1/20 0.35
ALDH1A1 P00352 2/20 0.34
CYP2D6 P10635 1/20 0.34
HSD17B10 Q99714 1/20 0.34
KIF11 P52732 1/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
ALOX15 P16050 1/20 0.33
RIPK1 Q13546 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22319094 0.79 MAPK1 (0.41) CYP2C19HIF1ATAAR1KCNN4MAPK1
SCHEMBL22730191 0.72 CYP2C19 (0.35) CYP2C19HIF1ATAAR1GRIN1GRIN2A
SCHEMBL22730161 0.71 CYP2C19 (0.34) CYP2C19HIF1ATAAR1GRIN1GRIN2A
SCHEMBL995710 0.68 KIF11 (0.42) CYP2C19HIF1ATAAR1GRIN1GRIN2A
SCHEMBL6682969 0.68 KIF11 (0.42) CYP2C19HIF1ATAAR1GRIN1GRIN2A
SCHEMBL3087077 0.68 KIF11 (0.42) CYP2C19HIF1ATAAR1GRIN1GRIN2A
SCHEMBL22730183 0.68 CYP2C19 (0.35) CYP2C19HIF1ATAAR1GRIN1GRIN2A
SCHEMBL22730174 0.68 MAPK1 (0.35) CYP2C19HIF1ATAAR1KCNN4MAPK1
SCHEMBL22734822 0.67 CYP2C19 (0.41) CYP2C19HIF1ATAAR1KCNN4MAPK1
SCHEMBL22734818 0.67 CYP2C19 (0.41) CYP2C19HIF1ATAAR1KCNN4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111164092-B Process for producing peptide compound 日产化学株式会社 2023-12-26 CN disclosed
US-20200291061-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NISSAN CHEMICAL CORPORATION (JP) 2020-09-17 US disclosed
EP-3693377-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND Nissan Chemical Corporation (JP) 2020-08-12 EP disclosed
CN-111164092-A Method for producing peptide compound 日产化学株式会社 2020-05-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200291061-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND VIP, NGLY1, IAPP CYP2C19 3871/4885HIF1A 1367/4885TAAR1 2433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.