Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | PRKX | P51817 | 1/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22319390 | 0.96 | PTGER4 (0.61) | PTGER4PTGER2MAPK14CYP3A4ROCK2 | |
| SCHEMBL22319352 | 0.91 | PTGER4 (0.70) | PTGER4PTGER2MAPK14CYP3A4ROCK2 | |
| SCHEMBL22319382 | 0.91 | PTGER4 (0.66) | PTGER4PTGER2PPARGPPARDPPARA | |
| SCHEMBL22319344 | 0.91 | PTGER4 (0.68) | PTGER4PTGER2MAPK14CYP3A4PPARG | |
| SCHEMBL22319358 | 0.90 | PTGER4 (0.65) | PTGER4PTGER2MAPK14CYP3A4PPARG | |
| SCHEMBL22319394 | 0.90 | PTGER4 (0.57) | PTGER4PTGER2MAPK14CYP3A4 | |
| SCHEMBL22319343 | 0.88 | PTGER4 (0.66) | PTGER4PTGER2PPARGPPARDPPARA | |
| SCHEMBL31028149 | 0.87 | PTGER4 (0.76) | PTGER4PTGER2MAPK14CYP3A4ROCK2 | |
| SCHEMBL22319348 | 0.87 | PTGER4 (0.76) | PTGER4PTGER2MAPK14CYP3A4ROCK2 | |
| SCHEMBL22319400 | 0.86 | PTGER4 (0.69) | PTGER4PTGER2PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11872226-B2 | N-benzyl-2-phenoxybenzamide derivatives as prostaglandin E2 (PGE2) receptors modulators | MEDIBIOFARMA, S.L. (ES) | 2024-01-16 | — | — | US | disclosed |
| US-20220117962-A1 | NEW N-BENZYL-2-PHENOXYBENZAMIDE DERIVATIVES AS PROSTAGLANDIN E2 (PGE2) RECEPTORS MODULATORS | MEDIBIOFARMA, S.L. (ES) | 2022-04-21 | — | — | US | disclosed |
| EP-3693359-A1 | NEW N-BENZYL-2-PHENOXYBENZAMIDE DERIVATIVES AS PROSTAGLANDIN E2 (PGE2) RECEPTORS MODULATORS | MEDIBIOFARMA, S.L. (ES) | 2020-08-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220117962-A1 | NEW N-BENZYL-2-PHENOXYBENZAMIDE DERIVATIVES AS PROSTAGLANDIN E2 (PGE2) RECEPTORS MODULATORS | PTGER2, PTGER4, PTGER1 | PTGER4 2/4885PTGER2 1/4885MAPK14 904/4885 |
| US-11872226-B2 | N-benzyl-2-phenoxybenzamide derivatives as prostaglandin E2 (PGE2) receptors modulators | PTGER2, PTGER4, PTGER1 | PTGER4 2/4885PTGER2 1/4885MAPK14 890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.