SCHEMBL2231944

SCHEMBL2231944

CC(C)O[SiH2]CCOCC1CO1

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
ALDH1A1 P00352 4/20 0.44
TDP1 Q9NUW8 1/20 0.44
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL830652 0.90 TSHR (0.55) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL8442252 0.88 TSHR (0.58) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL27967648 0.83 SMN1; SMN2 (0.49) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL4925410 0.79 TSHR (0.54) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL12215241 0.76 SMN1; SMN2 (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL28627231 0.76 SMN1; SMN2 (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL8512776 0.76 TSHR (0.54) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL28686409 0.75 SMN1; SMN2 (0.56) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL27840849 0.75 TSHR (0.48) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL14582472 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4702065-A1 POLYURETHANE ADHESIVES FOR ALUMINUM BONDING AS WELL OTHER SUBSTRATES ARKEMA FRANCE (FR) 2026-03-04 EP claimed
WO-2024226606-A1 POLYURETHANE ADHESIVES FOR ALUMINUM BONDING AS WELL OTHER SUBSTRATES ARKEMA FRANCE (FR) 2024-10-31 WO claimed
CN-120059762-A Liquid crystal aligning agent for forming weak anchor film, method for producing liquid crystal aligning film, and method for producing liquid crystal element JSR株式会社 2025-05-30 CN disclosed
US-10702467-B2 Emulsion containing organosilicon-based portions of hollow spheres L'ORÉAL (FR) 2020-07-07 US disclosed
US-20170304183-A1 EMULSION CONTAINING ORGANOSILICON-BASED PORTIONS OF HOLLOW SPHERES L'ORÉAL (FR) 2017-10-26 US disclosed
US-9622946-B2 Emulsion containing organosilicon-based portions of hollow spheres L'OREAL (FR) 2017-04-18 US disclosed
US-20130224267-A1 EMULSION CONTAINING ORGANOSILICON-BASED PORTIONS OF HOLLOW SPHERES L'OREAL (FR) 2013-08-29 US disclosed
EP-1932505-B1 W/O emulsion with a skin-correcting effect OREAL (FR) 2012-12-26 EP disclosed
EP-1579841-B1 Cosmetic composition comprising concave particles OREAL (FR) 2012-11-14 EP disclosed
US-20110217346-A1 EMULSION CONTAINING ORGANOSILICON-BASED PORTIONS OF HOLLOW SPHERES L'OREAL (FR) 2011-09-08 US disclosed
EP-2359908-A2 Cosmetic composition for lightening or unifying the complexion L'Oréal (FR) 2011-08-24 EP disclosed
EP-1349899-A2 TWO COMPONENT POLYURETHANE COATING COMPSITION CONTAINING EPOXY SILANE ADHESION PROMOTERS Bayer Corporation (US) 2003-10-08 EP disclosed
US-20030039846-A1 Two-component coating compositions containing silane adhesion promoters COVESTRO LLC 2003-02-27 US disclosed
US-20020119329-A1 Two-component coating compositions containing silane adhesion promoters BAYER CORPORATION 2002-08-29 US disclosed
WO-2002051899-A2 TWO COMPONENT POLYURETHANE COATING COMPOSITION CONTAINING EPOXY SILANE ADHESION PROMOTERS BAYER CORPORATION (US) 2002-07-04 WO disclosed
EP-0643752-B1 RESINOUS DENTAL COMPOSITION BASED ON POLYMERISABLE POLYSILOXANES PROCTER & GAMBLE (US) 1999-09-15 EP disclosed
US-5877232-A WEAR RESISTANCE; DIMENSIONAL STABILITY; SHRINKAGE INHIBITION THE PROCTER & GAMBLE COMPANY (US) 1999-03-02 US disclosed
EP-0643752-A1 RESINOUS DENTAL COMPOSITION BASED ON POLYMERISABLE POLYSILOXANES THE PROCTER & GAMBLE COMPANY (US) 1995-03-22 EP disclosed
EP-0643752-A4 RESINOUS DENTAL COMPOSITION BASED ON POLYMERISABLE POLYSILOXANES. PROCTER & GAMBLE (US) 1994-06-03 EP disclosed
WO-1993007230-A1 RESINOUS DENTAL COMPOSITION BASED ON POLYMERISABLE POLYSILOXANES THE PROCTER & GAMBLE COMPANY (US) 1993-04-15 WO disclosed