Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL830652 | 0.95 | TSHR (0.55) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL2231944 | 0.88 | TSHR (0.48) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL9869829 | 0.81 | TSHR (0.64) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL28627231 | 0.81 | SMN1; SMN2 (0.53) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL28617432 | 0.80 | SMN1; SMN2 (0.56) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL28690808 | 0.80 | TSHR (0.49) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL17442489 | 0.80 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL6051332 | 0.79 | SMN1; SMN2 (0.54) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL31426913 | 0.79 | TSHR (0.52) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL28262740 | 0.79 | TSHR (0.47) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5917075-A | Hydrolyzable and polymerizable silanes | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG, E.V. (DE) | 1999-06-29 | — | — | US | claimed |
| US-5917075-A | Hydrolyzable and polymerizable silanes | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG, E.V. (DE) | 1999-06-29 | — | — | US | disclosed |