Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | MVD | P53602 | 3/20 | 0.40 |
| ▸ | FDPS | P14324 | 2/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.36 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22319797 | 1.00 | BTN3A1 (0.45) | BTN3A1LMNABLMMVDFDPS | |
| SCHEMBL9555227 | 0.90 | LMNA (0.48) | LMNABLMFDPSGGPS1GSTO1 | |
| SCHEMBL9554689 | 0.90 | LMNA (0.48) | LMNABLMFDPSGGPS1GSTO1 | |
| SCHEMBL9555114 | 0.90 | LMNA (0.48) | LMNABLMFDPSGGPS1GSTO1 | |
| SCHEMBL9554941 | 0.90 | LMNA (0.48) | LMNABLMFDPSGGPS1GSTO1 | |
| SCHEMBL9555233 | 0.90 | LMNA (0.48) | LMNABLMFDPSGGPS1GSTO1 | |
| SCHEMBL9555371 | 0.86 | LMNA (0.48) | LMNABLMFDPSGGPS1GSTO1 | |
| SCHEMBL9555488 | 0.86 | LMNA (0.48) | LMNABLMFDPSGGPS1GSTO1 | |
| SCHEMBL12983932 | 0.86 | LMNA (0.48) | LMNABLMFDPSGGPS1GSTO1 | |
| SCHEMBL9555550 | 0.86 | LMNA (0.48) | LMNABLMFDPSGGPS1GSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200255841-A1 | HOST CELLS AND METHODS FOR REDUCING ISOPRENOID PRECURSORS AND ISOPRENOIDS BY GERANYLGERANYL REDUCTASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-13 | — | — | US | disclosed |