Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28279472 | 0.88 | ALOX15 (0.50) | ALOX15ALDH1A1FDFT1FNTAFNTB | |
| Squalene SCHEMBL23581966 | 0.82 | KMT2A (0.59) | PTPN1ALOX15ALDH1A1KDM1AKMT2A | |
| SCHEMBL22319793 | 0.82 | PTPN1 (0.57) | PTPN1KDM1AKMT2A | |
| SCHEMBL7946561 | 0.80 | PTPN1 (0.71) | PTPN1ALOX15KDM1AKMT2AMEN1 | |
| SCHEMBL30711116 | 0.80 | PTPN1 (0.71) | PTPN1ALOX15KDM1AKMT2AMEN1 | |
| SCHEMBL28820216 | 0.78 | PTPN1 (0.55) | PTPN1FDFT1KDM1ALSSPTPN2 | |
| Trans-Phytol SCHEMBL2066043 | 0.77 | PTPN1 (0.79) | PTPN1ALOX15ALDH1A1KDM1AKMT2A | |
| Trans-Phytol SCHEMBL4063116 | 0.77 | PTPN1 (0.79) | PTPN1ALOX15ALDH1A1KDM1AKMT2A | |
| SCHEMBL28279471 | 0.76 | ALOX15 (0.55) | ALOX15ALDH1A1FDFT1FNTAFNTB | |
| SCHEMBL24183169 | 0.76 | KMT2A (0.64) | ALOX15ALDH1A1FDFT1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200255841-A1 | HOST CELLS AND METHODS FOR REDUCING ISOPRENOID PRECURSORS AND ISOPRENOIDS BY GERANYLGERANYL REDUCTASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-13 | — | — | US | disclosed |