Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068033 | 1.00 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| Hydrochloric Acid SCHEMBL28060868 | 0.98 | MEN1 (0.53) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| Quinoline SCHEMBL28125384 | 0.95 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| Isoquinoline SCHEMBL28216430 | 0.87 | AR (0.47) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL24021437 | 0.86 | HTT (0.64) | ALDH1A1MEN1KMT2ACASP1AR | |
| SCHEMBL29845556 | 0.86 | HTT (0.64) | ALDH1A1MEN1KMT2ACASP1AR | |
| SCHEMBL249349 | 0.86 | HTT (0.64) | ALDH1A1MEN1KMT2ACASP1AR | |
| Quinoline SCHEMBL28128756 | 0.85 | HTT (0.59) | ALDH1A1MEN1KMT2ACASP1AR | |
| Hydrochloric Acid SCHEMBL3701824 | 0.84 | HTT (0.62) | ALDH1A1MEN1KMT2ACASP1AR | |
| SCHEMBL29406417 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ACASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182308-B1 | PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARM SPA (IT) | 2024-09-04 | — | — | EP | claimed |
| CN-109153636-A | Cyclopropyl-amide compound as dual LSD1/HDAC inhibitor | 朱比连特比利斯有限公司 | 2019-01-04 | — | — | CN | claimed |
| CN-108779104-A | Noval chemical compound for inhibiting Nampt and the composition comprising it | 延世大学校产学协力团 | 2018-11-09 | — | — | CN | claimed |
| CN-108430992-A | QUINOLINE-3-CARBOXAMIDES AS H-PGDS INHIBITORS | 阿斯特克斯医疗公司 | 2018-08-21 | — | — | CN | claimed |
| CN-105985335-B | Hydroxamic acid compound, preparation method and its usage | 成都地奥九泓制药厂 | 2018-06-08 | — | — | CN | claimed |
| CN-106458912-A | Bicyclic fused heteroaryl or aryl compounds and their use as IRAK4 mimetics | 辉瑞公司 | 2017-02-22 | — | — | CN | claimed |
| CN-105985335-A | Hydroxamic acid compound, preparation method and application thereof | 成都地奥九泓制药厂 | 2016-10-05 | — | — | CN | claimed |
| CN-103492377-B | As the triazolopyridine compounds of PIM kinase inhibitor | ARRAY BIOPHARMA INC. (US) | 2016-04-20 | — | — | CN | claimed |
| CN-105384685-A | New tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof | POLICHEM SA | 2016-03-09 | — | — | CN | claimed |
| CN-101910168-B | Tropane compounds | EXELIXIS INC | 2014-07-30 | — | — | CN | claimed |
| CN-101910168-A | Tropane compounds | EXELIXIS INC | 2010-12-08 | — | — | CN | claimed |
| CN-101429200-A | Tricyclic benzopyran compound as anti-arrhythmic agents | NISSAN CHEMICAL IND LTD (JP) | 2009-05-13 | — | — | CN | claimed |
| CN-1934116-A | Tricyclic benzopyran compounds useful as antiarrhythmic agents | NISSAN CHEMICAL IND LTD (JP) | 2007-03-21 | — | — | CN | claimed |
| CN-1867570-A | Isothiazoloquinolones and related compounds as anti-infective agents | ACHILLION PHARMACEUTICALS INC (US) | 2006-11-22 | — | — | CN | claimed |
| WO-2004019933-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| CN-1128790-C | 4-hydroxyquinoline-3-carboxamides and hydrazides as antiviral agents | UPJOHN CO (US) | 2003-11-26 | — | — | CN | claimed |
| EP-1299387-A1 | HETEROCYCLE CARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-04-09 | — | — | EP | claimed |
| WO-2002004445-A1 | HETEROCYCLE CARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-01-17 | — | — | WO | claimed |
| CN-1281439-A | 4-hydroxyquinoline-3-carboxamide and hydrazide compounds as antiviral agents | UPJOHN CO (US) | 2001-01-24 | — | — | CN | claimed |