SCHEMBL22320767

SCHEMBL22320767

B.c1ccc2c(c1)ccc1c2ccc2cccnc21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.62
MAPT P10636 4/20 0.60
CCR1 P32246 4/20 0.60
CCR8 P51685 4/20 0.60
CYP3A4 P08684 3/20 0.60
TSHR P16473 3/20 0.60
KDM4E B2RXH2 3/20 0.60
PMP22 Q01453 2/20 0.60
CCR5 P51681 2/20 0.60
TDP1 Q9NUW8 2/20 0.60
MMP2 P08253 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
GMNN O75496 1/20 0.60
TP53 P04637 1/20 0.60
HSP90AA1 P07900 1/20 0.60
CYP2D6 P10635 1/20 0.60
MMP9 P14780 1/20 0.60
ALOX15 P16050 1/20 0.60
NFKB1 P19838 1/20 0.60
MMP8 P22894 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30317540 1.00 LMNA (0.62) LMNAMAPTCCR1CCR8CYP3A4
SCHEMBL2061404 1.00 LMNA (0.62) LMNAMAPTCCR1CCR8CYP3A4
SCHEMBL686683 1.00 LMNA (0.62) LMNAMAPTCCR1CCR8CYP3A4
Hydrochloric Acid SCHEMBL27597963 0.98 LMNA (0.60) LMNAMAPTCCR1CCR8CYP3A4
1-Naphthoquinoline SCHEMBL15106 0.89 LMNA (0.69) LMNAMAPTCCR1CCR8CYP3A4
SCHEMBL17542434 0.89 CYP3A4 (0.59) LMNAMAPTCCR1CCR8CYP3A4
Phenanthrene SCHEMBL16685315 0.89 CCR1 (0.76) LMNAMAPTCCR1CCR8CYP3A4
1-Naphthoquinoline SCHEMBL29533982 0.89 LMNA (0.69) LMNAMAPTCCR1CCR8CYP3A4
SCHEMBL1246514 0.89 CCR1 (0.75) LMNAMAPTCCR1CCR8CYP3A4
1-Naphthoquinoline SCHEMBL6826374 0.87 LMNA (0.67) LMNAMAPTCCR1CCR8CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11539004-B2 Electroluminescent compound, thermally activated delayed fluorescence material, and application thereof WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2022-12-27 US disclosed
US-20200259088-A1 ELECTROLUMINESCENT COMPOUND, THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, AND APPLICATION THEREOF WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2020-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200259088-A1 ELECTROLUMINESCENT COMPOUND, THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, AND APPLICATION THEREOF TEAD2, TEAD1, TEAD4 LMNA 990/4885MAPT 147/4885CCR1 4856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.