Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22337572 | 0.82 | CDC42 (0.33) | — | |
| SCHEMBL27060029 | 0.78 | SMN1; SMN2 (0.34) | SMN1; SMN2ALDH1A1USP2HSD17B10GAA | |
| SCHEMBL2018376 | 0.78 | SMN1; SMN2 (0.34) | SMN1; SMN2ALDH1A1USP2HSD17B10GAA | |
| SCHEMBL20778981 | 0.68 | KDM4C (0.41) | SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL4700582 | 0.67 | USP2 (0.35) | SMN1; SMN2ALDH1A1USP2HSD17B10 | |
| SCHEMBL14655259 | 0.67 | USP2 (0.35) | SMN1; SMN2ALDH1A1USP2HSD17B10 | |
| SCHEMBL4704755 | 0.65 | EPHX1 (0.34) | SMN1; SMN2ALDH1A1USP2HSD17B10GAA | |
| SCHEMBL30689638 | 0.64 | GAA (0.34) | USP2HSD17B10GAA | |
| SCHEMBL5621635 | 0.63 | USP2 (0.33) | SMN1; SMN2USP2HSD17B10 | |
| SCHEMBL22322408 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12454523-B2 | Pyrazole derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2025-10-28 | — | — | US | disclosed |
| US-20230286954-A1 | PYRAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-09-14 | — | — | US | disclosed |
| US-11680057-B2 | Pyrazole derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-20 | — | — | US | disclosed |
| EP-3921306-A2 | PYRAZOLE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2021-12-15 | — | — | EP | disclosed |
| WO-2020161148-A2 | PYRAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286954-A1 | PYRAZOLE DERIVATIVES | RB1, NQO2, RBX1 | SMN1; SMN2 4149/4885ALDH1A1 1492/4885USP2 1163/4885 |
| US-11680057-B2 | Pyrazole derivatives | RB1, NQO2, RBX1 | SMN1; SMN2 4149/4885ALDH1A1 1492/4885USP2 1163/4885 |
| US-12454523-B2 | Pyrazole derivatives | RB1, NQO2, RBX1 | SMN1; SMN2 4149/4885ALDH1A1 1492/4885USP2 1163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.