Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANXA2 | P07355 | 8/20 | 0.68 |
| ▸ | S100A10 | P60903 | 8/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | FPR1 | P21462 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2236184 | 0.89 | ANXA2 (0.55) | ANXA2S100A10CYP2C19MEN1KMT2A | |
| SCHEMBL2233843 | 0.87 | ANXA2 (0.66) | ANXA2S100A10ALDH1A1MEN1KMT2A | |
| SCHEMBL2234809 | 0.87 | ANXA2 (0.65) | ANXA2S100A10ALDH1A1FPR1SMN1; SMN2 | |
| SCHEMBL2234993 | 0.81 | ANXA2 (0.65) | ANXA2S100A10ALDH1A1MEN1KMT2A | |
| SCHEMBL2232974 | 0.81 | ANXA2 (0.65) | ANXA2S100A10ALDH1A1 | |
| SCHEMBL2298299 | 0.80 | ANXA2 (0.67) | ANXA2S100A10ALDH1A1MEN1KMT2A | |
| SCHEMBL6115685 | 0.79 | RXFP1 (0.51) | ANXA2S100A10ALDH1A1HIF1AMEN1 | |
| SCHEMBL2233884 | 0.77 | ANXA2 (0.67) | ANXA2S100A10ALDH1A1MEN1KMT2A | |
| SCHEMBL2237790 | 0.75 | ANXA2 (0.68) | ANXA2S100A10ALDH1A1FPR1SMN1; SMN2 | |
| SCHEMBL3472780 | 0.73 | STS (0.59) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092505-A1 | S100 PROTEIN BINDING INTERACTION INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2011-08-04 | — | — | WO | claimed |
| WO-2011092505-A1 | S100 PROTEIN BINDING INTERACTION INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2011-08-04 | — | — | WO | disclosed |