Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANXA2 | P07355 | 17/20 | 0.65 |
| ▸ | S100A10 | P60903 | 17/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2234993 | 0.91 | ANXA2 (0.65) | ANXA2S100A10ALDH1A1 | |
| SCHEMBL2231482 | 0.91 | ANXA2 (0.58) | ANXA2S100A10ALDH1A1 | |
| SCHEMBL2235370 | 0.90 | ANXA2 (0.53) | ANXA2S100A10ALDH1A1MALT1 | |
| SCHEMBL2234809 | 0.90 | ANXA2 (0.65) | ANXA2S100A10ALDH1A1 | |
| SCHEMBL2233843 | 0.88 | ANXA2 (0.66) | ANXA2S100A10ALDH1A1 | |
| SCHEMBL2233884 | 0.88 | ANXA2 (0.67) | ANXA2S100A10ALDH1A1 | |
| SCHEMBL2236184 | 0.88 | ANXA2 (0.55) | ANXA2S100A10 | |
| SCHEMBL2236163 | 0.88 | ANXA2 (0.66) | ANXA2S100A10ALDH1A1 | |
| SCHEMBL2298299 | 0.87 | ANXA2 (0.67) | ANXA2S100A10ALDH1A1 | |
| SCHEMBL2236328 | 0.87 | ALDH1A1 (0.66) | ANXA2S100A10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092505-A1 | S100 PROTEIN BINDING INTERACTION INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2011-08-04 | — | — | WO | disclosed |