Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 6/20 | 0.59 |
| ▸ | CCR2 | P41597 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.51 |
| ▸ | ANXA2 | P07355 | 4/20 | 0.50 |
| ▸ | S100A10 | P60903 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12943495 | 0.88 | ALDH1A1 (0.59) | CCR1CCR2KDM4EHPGDRXFP1 | |
| SCHEMBL2232399 | 0.86 | CCR1 (0.54) | CCR1CCR2KDM4EHPGDRXFP1 | |
| SCHEMBL8776139 | 0.85 | RXFP1 (0.55) | CCR1KDM4EHPGDRXFP1ANXA2 | |
| SCHEMBL12943493 | 0.85 | RXFP1 (0.63) | CCR1CCR2KDM4EHPGDRXFP1 | |
| SCHEMBL934299 | 0.84 | CCR1 (0.51) | CCR1CCR2KDM4ERXFP1ANXA2 | |
| SCHEMBL16370574 | 0.82 | GAA (0.64) | CCR1CCR2KDM4EHPGDRXFP1 | |
| SCHEMBL6115917 | 0.82 | RXFP1 (0.55) | CCR1CCR2KDM4ERXFP1ANXA2 | |
| SCHEMBL10146036 | 0.82 | RXFP1 (0.69) | CCR1CCR2KDM4EHPGDRXFP1 | |
| SCHEMBL6116449 | 0.82 | RXFP1 (0.54) | CCR1CCR2KDM4ERXFP1ANXA2 | |
| SCHEMBL934178 | 0.81 | RXFP1 (0.52) | CCR1CCR2KDM4ERXFP1ANXA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092505-A1 | S100 PROTEIN BINDING INTERACTION INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2011-08-04 | — | — | WO | claimed |
| WO-2011092505-A1 | S100 PROTEIN BINDING INTERACTION INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2011-08-04 | — | — | WO | disclosed |