Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29509557 | 1.00 | EGFR (0.33) | EGFRERBB2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL31013177 | 0.73 | EGFR (0.34) | EGFRERBB2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL21412230 | 0.73 | EGFR (0.34) | EGFRERBB2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL22323635 | 0.72 | GAA (0.46) | CYP2C19TSHRGAANPC1NFKB1 | |
| SCHEMBL29509300 | 0.72 | GAA (0.46) | CYP2C19TSHRGAANPC1NFKB1 | |
| SCHEMBL24248699 | 0.72 | HSP90AA1 (0.37) | EGFRPOLB | |
| SCHEMBL28009643 | 0.71 | TSHR (0.41) | EGFRERBB2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL14125147 | 0.70 | PTGDR2 (0.42) | CYP3A4CYP2D6CYP2C19TSHRHIF1A | |
| SCHEMBL22323637 | 0.69 | NPC1 (0.36) | GAANPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL29509331 | 0.69 | NPC1 (0.36) | GAANPC1NFKB1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114007614-A | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2022-02-01 | — | — | CN | disclosed |
| EP-3920917-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | Skyhawk Therapeutics, Inc. (US) | 2021-12-15 | — | — | EP | disclosed |
| WO-2020163248-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2020-08-13 | — | — | WO | disclosed |