SCHEMBL28009643

SCHEMBL28009643

COCOc1ccc(Br)cc1OCOC

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C19 P33261 2/20 0.41
HIF1A Q16665 1/20 0.41
CYP2C9 P11712 1/20 0.40
TDP1 Q9NUW8 3/20 0.40
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPK1 P28482 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
EGFR P00533 1/20 0.38
ERBB2 P04626 1/20 0.38
HPGD P15428 3/20 0.38
PTGDR2 Q9Y5Y4 2/20 0.38
GLA P06280 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2178750 0.92 KDM4E (0.45) TSHRCYP3A4CYP2D6CYP2C19HIF1A
SCHEMBL5252344 0.92 KDM4E (0.45) TSHRCYP3A4CYP2D6CYP2C19HIF1A
SCHEMBL8996024 0.88 SMN1; SMN2 (0.46) TSHRCYP2C19CYP2C9TDP1KDM4E
SCHEMBL14125147 0.86 PTGDR2 (0.42) TSHRCYP3A4CYP2D6CYP2C19HIF1A
SCHEMBL2370519 0.86 MAPK1 (0.54) TSHRCYP3A4CYP2D6CYP2C19HIF1A
SCHEMBL23759950 0.84 CYP3A4 (0.37) TSHRCYP3A4CYP2D6CYP2C19HIF1A
SCHEMBL2618834 0.84 KDM4E (0.49) TSHRTDP1KDM4EALDH1A1HPGD
SCHEMBL981866 0.82 CYP3A4 (0.39) TSHRCYP3A4CYP2D6CYP2C19HIF1A
SCHEMBL30184562 0.82 ALDH1A1 (0.43) TSHRCYP3A4CYP2D6CYP2C19HIF1A
SCHEMBL25033177 0.82 ALDH1A1 (0.43) TSHRCYP3A4CYP2D6CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119371432-A Alpha-mangostin derivative and preparation method and application thereof 上海如凌生物医药有限公司 2025-01-28 CN disclosed
CN-102238948-B Novel 4-(heterocycloalkyl)benzene-1,3-diol compounds as tyrosinase inhibitors, process for the preparation thereof and use thereof in human medicine and also in cosmetics GALDERMA RES & DEV 2015-03-25 CN disclosed