Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 5/20 | 0.80 |
| ▸ | MAOA | P21397 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22325636 | 0.89 | STAT3 (0.63) | STAT3MAOAALDH1A1MAPTTDP1 | |
| SCHEMBL10037431 | 0.89 | STAT3 (1.00) | STAT3MAOAALDH1A1MAPTTDP1 | |
| SCHEMBL2801404 | 0.89 | STAT3 (1.00) | STAT3MAOAALDH1A1MAPTTDP1 | |
| SCHEMBL13843896 | 0.89 | STAT3 (0.84) | STAT3MAOAALDH1A1MAPTTDP1 | |
| SCHEMBL866692 | 0.89 | STAT3 (1.00) | STAT3MAOAALDH1A1MAPTTDP1 | |
| SCHEMBL22325626 | 0.86 | STAT3 (0.80) | STAT3MAOAALDH1A1MAPTTDP1 | |
| SCHEMBL22325634 | 0.86 | STAT3 (0.80) | STAT3MAOAALDH1A1MAPTTDP1 | |
| SCHEMBL10037444 | 0.86 | STAT3 (0.80) | STAT3MAOAALDH1A1MAPTTDP1 | |
| SCHEMBL10037445 | 0.84 | STAT3 (0.76) | STAT3MAOAALDH1A1MAPTTDP1 | |
| SCHEMBL22325662 | 0.83 | STAT3 (0.67) | STAT3MAOAALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020161959-A1 | NAPHTHOQUINONE COMPOUND HAVING ANTIBACTERIAL AND ANTIVIRAL ACTIVITIES AND PHARMACEUTICAL USE THEREOF | タヒボジャパン株式会社 | 2020-08-13 | — | — | WO | disclosed |
| WO-2020161959-A1 | NAPHTHOQUINONE COMPOUND HAVING ANTIBACTERIAL AND ANTIVIRAL ACTIVITIES AND PHARMACEUTICAL USE THEREOF | タヒボジャパン株式会社 | 2020-08-13 | — | — | WO | disclosed |